4 Results for "

Huh-7.5.1 cells

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Huh-7.5.1 cells" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N0248
CAS No.: 58316-41-9
Saikosaponin B2 is an antiviral and anticancer agent that regulates multiple transporters (such as various solute carriers and ATP-binding cassette transporters including MRP1, MRP2, and OCT2). Saikosaponin B2 is isolated from the plant glycoside component of the roots of Bupleurum scorzonerifolium. Saikosaponin B2 enhances the liver targeting of anticancer drugs via vinegar-baked Radix Bupleuri. Saikosaponin B2 inhibits HCV entry, replication, and translation, is effective against Daclatasvir (HY-10466)-resistant strains, and exerts a synergistic effect when used in combination with Daclatasvir. Saikosaponin B2 is commonly used in studies related to hepatocellular carcinoma and HCV infection .
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Cat. No.: HY-158073
CAS No.: 2943213-62-3
Target:  

SARS-CoV

Research Areas:  

Infection

ML2006a4 is an orally active inhibitor for SARS-CoV-2 main protease (M pro) with IC50 in picomolare value. ML2006a4 is cell permeable and antiviral active, that inhibits replication in SARS-CoV-2 in cells Huh7.5.1-ACE2-TMPRSS2 (Huh7.5.1++) in picomolare level
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Cat. No.: HY-113860
CAS No.: 101784-44-5
Target:  

HCV

Research Areas:  

Infection

Antiviral agent 52 (Compound 30) is a Chlorcyclizine (HY-112067) derivative that exhibits antiviral activity against hepatitic C virus (HCV) with an EC50 of 17 nM. Antiviral agent 52 reveals cytotoxicity in cell Huh7.5.1 with CC50 of 21.3 μM .
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Cat. No.: HY-115668
CAS No.: 956944-02-8
Target:  

HBV

Research Areas:  

Infection

NPD8716 is a sodium taurocholate cotransporting polypeptide (NTCP) inhibitor with a human IC50 of 17.8 μM. NPD8716 interacts with NTCP, blocks the binding of HBV preS1 to NTCP, impairs NTCP-mediated bile acid uptake, inhibits NTCP transporter activity, and blocks the attachment of viruses to host hepatocytes. NPD8716 inhibits the entry of HBV and HDV into host cells. NPD8716 can be used in studies related to hepatitis B virus infection and hepatitis D virus infection .
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