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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
IBET151
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "IBET151" in MCE Product Catalog:
30
30 Cited Publications
Synonyms: GSK1210151A
Target:
Áreas de investigación:
I-BET151 (GSK1210151A) is a BET bromodomain inhibitor which inhibits BRD4, BRD2, and BRD3 with pIC50 of 6.1, 6.3, and 6.6, respectively .
Referencia número: HY-110106
No. CAS: 1883545-47-8
Synonyms: GSK1210151A dihydrochloride
Target:
Áreas de investigación:
I-BET151 dihydrochloride (GSK1210151A dihydrochloride) is a BET bromodomain inhibitor which inhibits BRD4, BRD2, and BRD3 with pIC50 of 6.1, 6.3, and 6.6, respectively .
Referencia número: HY-173564
No. CAS: 2758171-54-7
Target:
Áreas de investigación:
DW34 is an orally active pan-BRD4-D1 biased inhibitor with additional BRD4-D2 inhibitive activity. DW34 displays comparable inhibitive efficacy to I-BET151 (HY-13235) (EC50 = 0.16 μM) with low nanomolar EC50 values of 0.14 μM. DW34 significantly reduces liver inflammation induced by LPS (HY-D1056) and APAP (HY-66005) via reducing chemokine expression and cellular necrosis .
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