2 Results for "

JH-RE-06

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "JH-RE-06" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-126214
CAS No.: 1361227-90-8
Purity:  99.87%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

JH-RE-06, a potent REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing recruitment of mutagenic POLζ. JH-RE-06 improves chemotherapy .
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Cat. No.: HY-126214S
Purity:  98.04%
JH-RE-06-d6 is deuterium labele JH-RE-06. JH-RE-06, a potent REV1-REV7 interface inhibitor (IC50=0.78 μM; Ki=0.42 μM), targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing recruitment of mutagenic POLζ. JH-RE-06 improves chemotherapy .
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