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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
KLHL19
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "KLHL19" in MCE Product Catalog:
4
4
4 Cited Publications
Cat. No.: HY-P75897
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KEAP1; Kelch-Like Protein 19; Kelch Like ECH Associated Protein 1; MGC10630; KLHL19; MGC20887; INrf2; MGC1114; Kelch-Like ECH-Associated Protein 1; MGC4407; KIAA0132; MGC9454; Kelch-Like Family Member 19; KEAP1 Delta C; Cytosolic Inhibitor Of Nrf2; INRF2
Species:
Human
Source:
Sf9 insect cells
2
2 Cited Publications
Cat. No.: HY-P702829
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KEAP1; Kelch-Like Protein 19; Kelch Like ECH Associated Protein 1; MGC10630; KLHL19; MGC20887; INrf2; MGC1114; Kelch-Like ECH-Associated Protein 1; MGC4407; KIAA0132; MGC9454; Kelch-Like Family Member 19; KEAP1 Delta C; Cytosolic Inhibitor Of Nrf2; INRF2
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-RS07230
Target:
Research Areas:
KEAP1 Human Pre-designed siRNA Set A contains three designed siRNAs for KEAP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
1
1 Cited Publications
Cat. No.: HY-P75899
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KEAP1; Kelch-Like Protein 19; Kelch Like ECH Associated Protein 1; MGC10630; KLHL19; MGC20887; INrf2; MGC1114; Kelch-Like ECH-Associated Protein 1; MGC4407; KIAA0132; MGC9454; Kelch-Like Family Member 19; KEAP1 Delta C; Cytosolic Inhibitor Of Nrf2; INRF2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-182927
KLHL12 ligand-1 is a KLHL12 Kelch domain ligand with a Ki of 0.33 μM, Ka of 0.33 μM, submicromolar binding affinity, and selective binding over KEAP1/KLHL19. KLHL12 ligand-1 binds in the substrate cleft of KLHL12, with its 4-methyl group forming a CH-π interaction with Tyr334. KLHL12 ligand-1 binds to cellular KLHL12 in permeabilized and intact cells, and has solvent-exposed positions suitable for modification to create PROTACs. KLHL12 ligand-1 can be used for the research of cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
