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KLHL19

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-182927

KLHL12 ligand-1	Others	Cancer
KLHL12 ligand-1 is a *KLHL12* Kelch domain ligand with a K_i of 0.33 μM, K_a of 0.33 μM, submicromolar binding affinity, and selective binding over *KEAP1/KLHL19*. KLHL12 ligand-1 binds in the substrate cleft of *KLHL12, with its 4-methyl group forming a CH-π interaction with Tyr334. KLHL12 ligand-1 binds to cellular KLHL12* in permeabilized and intact cells, and has solvent-exposed positions suitable for modification to create PROTACs. KLHL12 ligand-1 can be used for the research of cancer .

HY-RS07230

KEAP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
KEAP1 Human Pre-designed siRNA Set A contains three designed siRNAs for KEAP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

KEAP1 Human Pre-designed siRNA Set A KEAP1 Human Pre-designed siRNA Set A

Host:	Mouse (2) Rabbit (2)
Reactivity:	Human (4) Mouse (4)
Application:	IHC-P (2) ICC/IF (2) WB (4) FC (2) ELISA (2)
Isotype:	IgG (2) IgG1 (2)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84564

	Keap1 Antibody (YA4261) INrf2; KLHL19	WB, ICC/IF, FC, ELISA	Human, Mouse
	Keap1 Antibody (YA4261) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Keap1.

HY-P84564A

	Keap1 Antibody (YA4261)(PBS only) INrf2; KLHL19	WB, ICC/IF, FC, ELISA	Human, Mouse
	Keap1 Antibody (YA4261) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Keap1.

HY-P80732

	Keap1 Antibody (YA324) 3 Publications Verification INrf2; KLHL19	WB, IHC-P	Human, Mouse
	Keap1 Antibody (YA324) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Keap1.

HY-P80732A

	Keap1 Antibody (YA324)(PBS only) INrf2; KLHL19	WB, IHC-P	Human, Mouse
	Keap1 Antibody (YA324) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Keap1.

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KEAP1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
KEAP1 Human Pre-designed siRNA Set A contains three designed siRNAs for KEAP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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