1 Result for "

KVS0001

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KVS0001" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-161111
CAS No.: 3056394-59-0
Target:  

Ser/Thr Kinase

Research Areas:  

Cancer

KVS0001 is a selective SMG1 inhibitor. KVS0001 elevates the expression of transcripts and proteins resulting from truncating mutations. KVS0001 increased the presentation of immune-targetable HLA class I-associated peptides from nonsense-mediated decay (NMD)-downregulated proteins on the surface of cancer cells. KVS0001 exerts anti-tumor properties and can be studied in research for NMD-related diseases, including cancer and inherited diseases .
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