1 Result for "

Keap1-Nrf2-IN-25

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Keap1-Nrf2-IN-25" in MCE Product Catalog:

Cat. No.: HY-168922
CAS No.: 3100306-80-4
Keap1-Nrf2-IN-25 (Compound 19) is a potent Keap1-Nrf2 inhibitor (IC50 of 0.55 μM) with Keap1 binding affinity (Kd of 0.50 μM). Keap1-Nrf2-IN-25 activates Nrf2, reduces ROS and pro-inflammatory cytokines (IL-1β, IL-6). Keap1-Nrf2-IN-25 exerts protective effects against DSS (HY-116282)-induced colitis .
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