2 Results for "

LUF7996

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "LUF7996" in MCE Product Catalog:

Cat. No.: HY-180571
CAS No.: 3104736-80-0
Target:  

PROTACs CCR

Research Areas:  

Cancer

LUF7996 is a CCR2 PROTAC Degrader degrading CCR2 with DC50 = 2.6 μM. LUF7996 demonstrates engagement of both and the E3 ligase cereblon and displays sustain and concentration-dependent degradation of CCR2. LUF7996 reliance on the lysosomal pathway to induce CCR2 degradation. LUF7996 efficiently inhibits monocyte migration in virto .
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Cat. No.: HY-180572
CAS No.: 1350765-28-4
Research Areas:  

Cancer

CCR2 ligand-1 is a ligand for CCR2. CCR2 ligand-1 conjugates with the Linker PIN1 degrader-3 (HY-79577) and the E3 ligase ligand Thalidomide 4-fluoride (HY-41547) can be used for the synthesis of LUF7996 (HY-180571) .
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