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LUF7996

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-180571
    LUF7996

    		PROTACs CCR Cancer
    LUF7996 is a CCR2 PROTAC Degrader degrading CCR2 with DC50 = 2.6 μM. LUF7996 demonstrates engagement of both and the E3 ligase cereblon and displays sustain and concentration-dependent degradation of CCR2. LUF7996 reliance on the lysosomal pathway to induce CCR2 degradation. LUF7996 efficiently inhibits monocyte migration in virto .
    LUF7996
  • HY-180572
    CCR2 ligand-1

    		Ligands for Target Protein for PROTAC CCR Cancer
    CCR2 ligand-1 is a ligand for CCR2. CCR2 ligand-1 conjugates with the Linker PIN1 degrader-3 (HY-79577) and the E3 ligase ligand Thalidomide 4-fluoride (HY-41547) can be used for the synthesis of LUF7996 (HY-180571) .
    CCR2 ligand-1

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