1 Result for "

LY 237

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LY 237" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-178234
CAS No.: 1892576-07-6
Target:  

GPR84

Research Areas:  

Inflammation/Immunology

LY237 is a potent GPR84 full agonist, with EC50 values of 0.189 nM and 0.07 nM in cAMP inhibition assay and calcium flux assay, respectively. LY237 binds to the amphipathic orthosteric pocket of GPR84, stabilizes the active conformation of the receptor, and promotes its coupling with Gαi protein. LY237 can be used in research related to ulcerative colitis, fibrotic diseases, non-alcoholic steatohepatitis, and acute respiratory distress syndrome .
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