1 Result for "

Ligustrazine (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Ligustrazine (Standard)" in MCE Product Catalog:

Ligustrazine (Standard)
Ligustrazine (Standard)
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Cat. No.: HY-N0264R
CAS No.: 1124-11-4
Synonyms: Chuanxiongzine (Standard); Tetramethylpyrazine (Standard)
Category:  

Natural Products Dicerothamnus rhinocerotis Plants Umbelliferae

Target:  

Reference Standards Reactive Oxygen Species (ROS) Akt NO Synthase Aminotransferases (Transaminases)

Ligustrazine (Standard) (Chuanxiongzine (Standard)) is the analytical standard of Ligustrazine (HY-N0264). This product is intended for research and analytical applications. Ligustrazine (Chuanxiongzine) is an orally active, blood-brain barrier-permeable alkaloid. It can be isolated from Ligusticum striatum DC. Ligustrazine reduces ROS, upregulates the levels of p-Akt/Akt and p-eNOS/eNOS, and decreases ALT and AST. It inhibits glutamate excitotoxicity, calcium overload, oxidative stress, ischemia-reperfusion injury and atherosclerotic plaque progression, enhances synaptic plasticity, and improves neurological function, cerebral infarct volume and brain water content. Ligustrazine possesses anti-inflammatory, antioxidant, lipid-lowering, endothelial protective and hepatoprotective activities. It can be used in studies related to ischemic stroke, cerebral ischemia-reperfusion injury and atherosclerosis .
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