1124-11-4
Chemical Structure
Ligustrazine
Synonym(s): Chuanxiongzine; Tetramethylpyrazine
- CAS No.: 1124-11-4
- Formula:C8H12N2
- Molecular Weight:136.19
IUPAC Name: 2,3,5,6-tetramethylpyrazine
InChIKey: FINHMKGKINIASC-UHFFFAOYSA-N
SMILES: CC1=C(C)N=C(C)C(C)=N1
Biological Activity: Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong)[1], is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats[2][3].
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Ligustrazine | 99.99% | Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong), is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats. | ||||||||||||||||||||
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Ligustrazine (Standard) | 99.99% | Ligustrazine (Standard) is the analytical standard of Ligustrazine. This product is intended for research and analytical applications. Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong), is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats. | ||||||||||||||||||||
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- [1]. Zhao Y, et al. Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective. Oxid Med Cell Longev. 2016;2016:2124638. [Content Brief]
- [2]. Wu W, et al. Tetramethylpyrazine protects against scopolamine-induced memory impairments in rats by reversing the cAMP/PKA/CREB pathway. Behav Brain Res. 2013 Sep 15;253:212-6. [Content Brief]
- [3]. Kao TK, et al. Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. Exp Neurol. 2013 Sep;247:188-201. [Content Brief]
Keywords