Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
MAP3K12
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "MAP3K12" in MCE Product Catalog:
Target:
Research Areas:
DLK-IN-1 (Compound 14) is an orally active, blood-brain barrier-penetrable and selective inhibitor of dual leucine zipper kinase (DLK, MAP3K12) with a Ki value of 3 nM. DLK-IN-1 inhibits Flt3, PAK4, STK33 and TrkA. DLK-IN-1 reduces p-c-Jun. DLK-IN-1 can be used in Alzheimer's disease research .
Cat. No.: HY-RS08049
Target:
Research Areas:
MAP3K12 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP3K12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-170484
Research Areas:
KAI-11101 is the inhibitor for dual leucine zipper kinase (DLK, MAP3K12) with a Ki of 0.7 nM. KAI-11101 inhibits Paclitaxel (HY-B0015)-induced cJun phosphorylation (IC50=95 nM) and thus inhibits the activation of MAPK pathway. KAI-11101 is blood brain barrier penetrable and can be further investigated for its neuroprotective property .
Cat. No.: HY-P70921
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MBIP; MUK-Binding Inhibitory Protein; MAP3K12 Binding Inhibitory Protein 1; CDNA, FLJ96307, Homo Sapiens MAP3K12 Binding Inhibitory Protein 1 (MBIP), MRNA; MAPK Upstream Kinase-Binding Inhibitory Protein; MAP3K12 Binding Inhibitory Protein 1, Isoform CRA_
Species:
Human
Source:
E. coli
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
