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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
MC-GGFG-DXD
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "MC-GGFG-DXD" in MCE Product Catalog:
32
32 Cited Publications
Synonyms: MC-GGFG-DXD
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Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
Cat. No.: HY-13631EG
CAS No.: 1599440-13-7
Synonyms: MC-GGFG-DXD (GMP)
Cat. No.: HY-176415
CAS No.: 3025787-83-8
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Cys-MC-GGFG-Dxd is a cysteine-modified, cleavable ADC drug-linker conjugate. Cys-MC-GGFG-Dxd consists of a maleimidocaproyl-glycine-glycine-L-phenylalanine-glycine (MC-GGFG) linker and an Exatecan (HY-13631) derivative (DXd) (HY-13631D) payload. Cys-MC-GGFG-Dxd can be further conjugated to anti-HER2 IgG1κ antibody for the synthesis of antibody-drug conjugates (ADC), such as the breast cancer-targeting ADC compound Fam-trastuzumab deruxtecan-nxki (Enhertu) .
Cat. No.: HY-P3669
CAS No.: 200427-88-9
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Cat. No.: HY-P1449
CAS No.: 187794-49-6
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Cat. No.: HY-13631ES4
Synonyms: MC-GGFG-DXD-d5
Cat. No.: HY-P4192
CAS No.: 1817857-75-2
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Cat. No.: HY-13631ES3
CAS No.: 2760715-87-3
Synonyms: MC-GGFG-DXD-d2
Cat. No.: HY-P11295
CAS No.: 3035272-00-2
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Cat. No.: HY-13631ES
CAS No.: 2760715-91-9
Synonyms: MC-GGFG-DXD-d4
Cat. No.: HY-176415S
Cat. No.: HY-13631ES1
CAS No.: 2760715-89-5
Synonyms: MC-GGFG-DXD-d6
Cat. No.: HY-13631ES2
CAS No.: 2760715-88-4
Synonyms: MC-GGFG-DXD-d4-1
Cat. No.: HY-P1449A
CAS No.: 2450273-39-7
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Cat. No.: HY-176415S1
Synonyms: Cys-MC-GGFG-DXD-d5 TFA
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
