2760715-87-3
Chemical Structure
Deruxtecan-d2
Synonym(s): MC-GGFG-DXD-d2
- CAS No.: 2760715-87-3
- Formula:C52H54D2FN9O13
- Molecular Weight:1036.06
IUPAC Name: 3-(1-chloroethyl)-5-(trifluoromethyl)aniline
InChIKey: WXNSCLIZKHLNSG-YPYPAOJXSA-N
SMILES: O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOC([2H])([2H])C(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O
Biological Activity: Deruxtecan-d2 is the deuterium labeled Deruxtecan (HY-13631E)[1]. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
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Deruxtecan-d2 | 97.45% | Deruxtecan-d2 is the deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402. | ||||||||||||||||||||
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Deruxtecan (GMP) | Deruxtecan (GMP) (MC-GGFG-DXD (GMP)) is Deruxtecan (HY-13631E) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813). | |||||||||||||||||||||
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Deruxtecan-d5 | 98.40% | Deruxtecan-d5 is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402. | ||||||||||||||||||||
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Deruxtecan-d4-1 | Deruxtecan-d4-1 is the deuterium labeled Adenosine Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402. | |||||||||||||||||||||
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Deruxtecan-d6 | Deruxtecan-d6 is the deuterium labeled Deruxtecan. | |||||||||||||||||||||
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Deruxtecan-d4 | 97.01% | Deruxtecan-d4 is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402. | ||||||||||||||||||||
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Deruxtecan | 99.84% | Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813). | ||||||||||||||||||||
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