(1R)-Deruxtecan
Based on 1 Customer Validation
(1R)-Deruxtecan is a drug-linker conjugates for ADC.
For research use only. We do not sell to patients.
- Purity: 99.32%
- CAS No.: 2270986-87-1
- Formula: C52H56FN9O13
- Molecular Weight:1034.05
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2270986-87-1
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Appearance Solid
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Molecular Weight 1034.05
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Formula C52H56FN9O13
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Color Light yellow to brown
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SMILES
CC[C@]1(C(OCC2=C1C=C3C4=C(C5=C6C(C=C(C(C)=C6CC[C@H]5NC(COCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN7C(C=CC7=O)=O)=O)=O)=O)CC8=CC=CC=C8)=O)=O)=O)F)=N4)CN3C2=O)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (96.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9671 mL | 4.8354 mL | 9.6707 mL | 24.1768 mL |
| 5 mM | 0.1934 mL | 0.9671 mL | 1.9341 mL | 4.8354 mL | |
| 10 mM | 0.0967 mL | 0.4835 mL | 0.9671 mL | 2.4177 mL | |
| 15 mM | 0.0645 mL | 0.3224 mL | 0.6447 mL | 1.6118 mL | |
| 20 mM | 0.0484 mL | 0.2418 mL | 0.4835 mL | 1.2088 mL | |
| 25 mM | 0.0387 mL | 0.1934 mL | 0.3868 mL | 0.9671 mL | |
| 30 mM | 0.0322 mL | 0.1612 mL | 0.3224 mL | 0.8059 mL | |
| 40 mM | 0.0242 mL | 0.1209 mL | 0.2418 mL | 0.6044 mL | |
| 50 mM | 0.0193 mL | 0.0967 mL | 0.1934 mL | 0.4835 mL | |
| 60 mM | 0.0161 mL | 0.0806 mL | 0.1612 mL | 0.4029 mL | |
| 80 mM | 0.0121 mL | 0.0604 mL | 0.1209 mL | 0.3022 mL |