1 Result for "

MCUF651

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MCUF651" in MCE Product Catalog:

Cat. No.: HY-149453
CAS No.: 2747162-85-0
Purity:  99.85%
Target:  

Guanylate Cyclase

Research Areas:  

Cardiovascular Disease

MCUF-651 is an orally active guanylyl cyclase A receptor (GC-A) positive allosteric modulator (PAM) (KD: 397 nM ). MCUF-651 binds to GC-A and selectively enhances the binding of atrial natriuretic peptide (ANP) to GC-A. MCUF-651 enhances ANP-mediated cGMP generation in human cardiac, renal, and fat cells. MCUF-651 inhibits cardiomyocyte hypertrophy .
loading...
    loading...