1 Result for "

MET/PDGFRA-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MET/PDGFRA-IN-1" in MCE Product Catalog:

Cat. No.: HY-149510
CAS No.: 3125694-48-3
Target:  

c-Met/HGFR Apoptosis PDGFR

Research Areas:  

Cancer

MET/PDGFRA-IN-1 (compound 8c) is a MET and PDGFRA protein inhibitor (IC50: 36 μM for MET). MET/PDGFRA-IN-1 inhibits MET phosphorylation and induces cell apoptosis. MET/PDGFRA-IN-1 inhibits proliferation of MET-positive cells (IC50s: 15.3, 19.0, 22.0, 25.6, 21.0, 31.5 μM for AsPc-1, EBC-1, MKN-45, Mia-Paca-2, HT-29, K562 cells respectively) .
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