MET/PDGFRA-IN-1
MET/PDGFRA-IN-1 (compound 8c) is a MET and PDGFRA protein inhibitor (IC50: 36 μM for MET). MET/PDGFRA-IN-1 inhibits MET phosphorylation and induces cell apoptosis. MET/PDGFRA-IN-1 inhibits proliferation of MET-positive cells (IC50s: 15.3, 19.0, 22.0, 25.6, 21.0, 31.5 μM for AsPc-1, EBC-1, MKN-45, Mia-Paca-2, HT-29, K562 cells respectively).
For research use only. We do not sell to patients.
- CAS No.: 3125694-48-3
- Formula: C26H23N7O
- Molecular Weight:449.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PDGFRα |
Chemical Information
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CAS No. 3125694-48-3
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Molecular Weight 449.51
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Formula C26H23N7O
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SMILES
CC1=CC=C(C=C1)CN2N=NC(COC3=CC=C(C=C3)/C=N/NC4=C5C=CC=CC5=NC=N4)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MET/PDGFRA-IN-1 Related Classifications
HY-149510 Related Classifications
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