2 Results for "

MS-5 cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MS-5 cells" in MCE Product Catalog:

Cat. No.: HY-175780
CAS No.: 1465291-19-3
Research Areas:  

Cancer

CD28-IN-1 (Compound 19MS-5) is a CD28 inhibitor with a KD of 12.48  μM. CD28-IN-1 has a superior binding capacity to CD28 and potently inhibits CD28-B7 interactions. CD28-IN-1 inhibits CD28-driven immune activation and suppresses cytokine (IFN-γ, IL-2 and TNF-α) production in primary human T cells co-cultured with tumor spheroids and human epithelial tissues. CD28-IN-1 can be used for tumor immunity research .
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Cat. No.: HY-P11728
CAS No.: 1643580-44-2
Target:  

CXCR Apoptosis Caspase Akt ERK

Research Areas:  

Cancer

Peptide E5 is an antagonist targeting the CXCR4/CXCL12 axis. Peptide E5 blocks the CXCR4/CXCL12 axis, downregulates CXCR4 expression, and inhibits the phosphorylation of downstream Akt and Erk. Peptide E5 induces apoptosis, suppresses migration and adhesion of breast cancer cells. Peptide E5 inhibits CXCL12-mediated endothelial progenitor cell recruitment, thereby suppressing tumor angiogenesis. Peptide E5 is applicable to relevant research on breast cancer .
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