CD28-IN-1
CD28-IN-1 (Compound 19MS-5) is a CD28 inhibitor with a KD of 12.48 μM. CD28-IN-1 has a superior binding capacity to CD28 and potently inhibits CD28-B7 interactions. CD28-IN-1 inhibits CD28-driven immune activation and suppresses cytokine (IFN-γ, IL-2 and TNF-α) production in primary human T cells co-cultured with tumor spheroids and human epithelial tissues. CD28-IN-1 can be used for tumor immunity research.
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- No. CAS: 1465291-19-3
- Fòrmula: C16H17N3O4
- Peso molecular:315.32
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
IL-2 |
Chemical Information
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No. CAS 1465291-19-3
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Peso molecular 315.32
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Fòrmula C16H17N3O4
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SMILES
O=C1N(C)C2=CC=CC(C(OCCC3=C(C)NN=C3C)=O)=C2O1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CD28-IN-1 Related Classifications
HY-175780 Related Classifications
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