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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Membrane Order
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Membrane Order" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-D1428
CAS No.: 797785-10-5
Cat. No.: HY-P2530
CAS No.: 187987-64-0
Cat. No.: HY-162160
CAS No.: 1221739-85-0
Cat. No.: HY-164267
CAS No.: 121999-55-1
Synonyms: SM (d18:1/14:0)
Target:
Research Areas:
Sphingomyelin (d18:1,C14:0), a major sphingolipid in mammalian cells, increases membrane molecular order .
Cat. No.: HY-185564
CAS No.: 118680-70-9
Target:
Research Areas:
F6OM, a nonionic fluorinated octyl maltoside derivative, is a surfactant. F6OM readily interacts with and completely solubilizes phospholipid vesicles via a heterogeneous solubilization mechanism, without compromising membrane order at subsolubilizing concentrations. F6OM promotes bilayer insertion of an integral membrane enzyme in the absence of micelles to support functional refolding of integral membrane proteins. F6OM can be used for membrane-protein applications .
Cat. No.: HY-DY1089
CAS No.: 797785-10-5
Solvent and concentration: DMSO: 5 mM
Cat. No.: HY-D3091
CAS No.: 2757681-99-3
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Research Areas:
NRLyso is a lysosome-targeted solvatochromic fluorescent probe derived from Nile Red (HY-D0718). It can localize to lysosomes and is applicable for imaging lysosomal lipid order and polarity. The excitation wavelength of NRLyso is 520 nm, and its emission maximum varies with the environment. NRLyso partitions well into lipid membranes: it exhibits fluorescence enhancement and emission blue-shift in low-polarity, tightly packed lipid environments, while shows emission red-shift in more polar, disordered lipid environments. NRLyso maintains organelle specificity under oxidative and hyperosmotic stress conditions, and can detect changes in lysosomal lipid order and polarity in response to these stresses, cholesterol extraction, and cholesterol enrichment .
Cat. No.: HY-D3092
CAS No.: 2757682-01-0
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Research Areas:
NRERf is an endoplasmic reticulum (ER)-targeted solvatochromic fluorescent probe based on Nile Red (HY-D0718). It possesses ER-targeting capability and can sense changes in local polarity and lipid order of biological membranes. NRERf undergoes excited-state charge transfer, with its emission color changing according to local polarity: the tightly packed, low-polarity liquid-ordered phase (Lo) induces a blue-shifted emission, while the high-polarity liquid-disordered phase (Ld) induces a red-shifted emission. The emission wavelength of NRERf varies with the environment. NRERf can be used to detect changes in lipid order and polarity induced in the ER by cholesterol extraction/enrichment, oxidative stress, and hyperosmotic shock .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
