2757682-03-2
Chemical Structure
NRGolgi
- CAS No.: 2757682-03-2
- Formula:C38H52N4O4
- Molecular Weight:628.84
InChIKey: BXLCQPQQKORVSC-UHFFFAOYSA-N
SMILES: O=C(NCCNC(CCCN(C1=CC=C2N=C3C(OC2=C1)=CC(C4=C3C=CC=C4)=O)CC)=O)CCCCCCCCCCCCC
Biological Activity: NRGolgi is a Nile Red-based solvatochromic fluorescent probe targeted to the Golgi apparatus. NRGolgi localizes selectively to the Golgi membrane via its myristic acid group, and leverages the property of its emission wavelength undergoing blue/red shift with local polarity to quantitatively detect the lipid order of the Golgi membrane in living cells using dual-emission ratiometric imaging (550-600 nm / 600-650 nm). NRGolgi is suitable for real-time monitoring of Golgi lipid order under conditions of oxidative stress, mechanical stress, and altered cholesterol metabolism[1].
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NRGolgi | NRGolgi is a Nile Red-based solvatochromic fluorescent probe targeted to the Golgi apparatus. NRGolgi localizes selectively to the Golgi membrane via its myristic acid group, and leverages the property of its emission wavelength undergoing blue/red shift with local polarity to quantitatively detect the lipid order of the Golgi membrane in living cells using dual-emission ratiometric imaging (550-600 nm / 600-650 nm). NRGolgi is suitable for real-time monitoring of Golgi lipid order under conditions of oxidative stress, mechanical stress, and altered cholesterol metabolism. | |||||||||||||||||||||
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