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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
Metal chelation
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "Metal chelation" in MCE Product Catalog:
4
Target:
Cat. No.: HY-Y0091
CAS No.: 161265-03-8
Synonyms: 9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene
Cat. No.: HY-N4084
CAS No.: 271579-11-4
Category:
Thonningia sanguinea Phenols Polyphenols Plants Disease Research Fields Balanophoraceae Cancer
Target:
Cat. No.: HY-126404
CAS No.: 65072-00-6
Research Areas:
Casein hydrolysate is an orally effective, multi-functional mixture of bioactive peptides, a hydrolysis product of casein (HY-125865), containing ACE inhibitors and immunomodulatory target regulators, among others. Casein hydrolysate releases short-chain bioactive peptides through enzymatic hydrolysis of casein, increasing cellular glutathione and catalase levels, enhancing ConA-induced IL-2 production, and exhibiting metal ion chelation, free radical scavenging, antibacterial, and mineral absorption-promoting effects. Casein hydrolysate lowers blood pressure by inhibiting angiotensin-converting enzyme (ACE) and reducing bradykinin degradation .
Cat. No.: HY-W110927
CAS No.: 130-22-3
Category:
Human Gut Microbiota Metabolites Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W717743
CAS No.: 913528-04-8
Cat. No.: HY-B1610K
Cat. No.: HY-N2362S2
CAS No.: 53795-94-1
Synonyms: DL-2-Aminopropionic acid-d3
Cat. No.: HY-120420
CAS No.: 167695-87-6
Research Areas:
N4Py is a bleomycin-mimetic pentadentate ligand that targets intracellular FeII and reversibly chelates a variety of transition metals. N4Py chelates induce apoptosis through two pathways: DNA cleavage via ROS generation and XIAP downregulation via ZnII chelation, with only FeII/FeIII-N4Py exhibiting potent DNA cleavage activity. The folate conjugate of N4Py targets folate receptors, can be intracellularly cleaved, and selectively kills FR-positive cancer cells. N4Py can be used in research on various cancers including nasopharyngeal epidermoid carcinoma, ovarian cancer, and mammary adenocarcinoma .
Cat. No.: HY-W110896
CAS No.: 2411-89-4
Synonyms: Phthalein Purple
Cat. No.: HY-116454
CAS No.: 1312345-89-3
Target:
Research Areas:
GSK5750 is a specific and potent HIV-1 reverse transcriptase ribonuclease H inhibitor with an IC50 value of 0.33 μM. GSK5750 is bound at the RNase H active site through a metalion chelation mechanism .
Cat. No.: HY-162760
CAS No.: 2987884-27-3
Target:
Research Areas:
COMT-IN-1 (compound C12), a nitrophenolic analogue, is an orally active dopamine metabolic enzyme catechol-O-methyltransferase (COMT) inhibitor with IC50s of 0.37 μM, 95.58 μM and 58.82 μM for COMT, MAO-A and MAO-B, respectively. COMT-IN-1 exhibits chelation with a variety of metal ions. COMT-IN-1 exhibits good BBB permeability. COMT-IN-1 improves dopamine levels and ameliorates MPTP (HY-15608)-induced Parkinson's disease (PD) symptoms in mice .
Cat. No.: HY-170650
CAS No.: 33017-85-5
Research Areas:
SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase enzyme (SMase) inhibitor (IC50 value for B. cereus SMase is 6.43 µM). SMase-IN-1 also inhibits eqBuChE (59.50% inhibition rate at 50 µM concentration). SMase-IN-1 forms a complex with Cu 2+ in biometal interactions. SMase-IN-1 reduces B. cereus-induced hemolysis on sheep erythrocytes .
Cat. No.: HY-164055
CAS No.: 202828-10-2
Target:
Research Areas:
HL1 is a Schiff base ligand. HL1 exhibits chelation-enhanced fluorescence effect when forming complexes and can be used as a fluorescent probe for metal ions. HL1 can be used for the research of cancer .
Cat. No.: HY-W011060R
CAS No.: 23978-09-8
Synonyms: 4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane (Standard)
Cat. No.: HY-121315
CAS No.: 1550053-19-4
Target:
Research Areas:
BRD4097 is an inhibitor of histone deacetylase (HDAC). BRD4097 acts by inhibiting the activity of HDACs, especially HDAC 1,2 and 3, through metal chelation and spatial rejection mechanisms, and this inhibition may help regulate gene expression and alter chromatin structure, thereby affecting a variety of biological processes. BRD4097 is used to study the role of HDAC in cholesterol metabolism and NPC1 diseases .
Cat. No.: HY-174272
Research Areas:
GSK-3β inhibitor 27 (Compound 1c) is a reversible and competitive GSK-3β inhibitor with an IC50 value of 2.2 μM. GSK-3β inhibitor 27 inhibits tau hyperphosphorylation, reduces Aβ protein aggregation and possesses metal chelation and neuroprotective potential. GSK-3β inhibitor 27 is promising for research of neurodegenerative diseases (such as Alzheimer’s disease) .
Cat. No.: HY-N2362S5
CAS No.: 71261-64-8
Synonyms: DL-2-Aminopropionic acid-15N
Cat. No.: HY-N2362S
CAS No.: 102029-81-2
Synonyms: DL-2-Aminopropionic acid-13C-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
