130-22-3
130-22-3
Chemical Structure
Alizarin Red S sodium
Synonym(s): ARS sodium
- CAS No.: 130-22-3
- Formula:C14H7NaO7S
- Molecular Weight:342.26
IUPAC Name: sodium 3,4-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
InChIKey: HFVAFDPGUJEFBQ-UHFFFAOYSA-M
SMILES: O=S(C(C=C1C2=O)=C(O)C(O)=C1C(C3=C2C=CC=C3)=O)(O[Na])=O
Biological Activity: Alizarin Red S sodium is an anthraquinone derivative dye. When combined with cations such as calcium ions, the functional group of Alizarin Red S sodium can form a coordination bond with the cation through the oxygen atom to show orange-red fluorescence. Alizarin Red S sodium can be used for screening of calcium compounds in synovial fluid and detecting osteoblast differentiation, and can also be used for bone staining in mice. Excitation/emission wavelength: 500/570 nm[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Alizarin Red S sodium | 95.0% | Alizarin Red S sodium is an anthraquinone derivative dye. When combined with cations such as calcium ions, the functional group of Alizarin Red S sodium can form a coordination bond with the cation through the oxygen atom to show orange-red fluorescence. Alizarin Red S sodium can be used for screening of calcium compounds in synovial fluid and detecting osteoblast differentiation, and can also be used for bone staining in mice. Excitation/emission wavelength: 500/570 nm. | ||||||||||||||||||||
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Alizarin Red S Indicator (4.3-6.3), IND | 95% | Alizarin red S indicator (C.I. 58005) is a reductively active (quinone-based) anthraquinone dye that forms complexes with metal ions (such as zirconium, calcium) or boric acid to label calcium deposition and perform electrochemical sensing functions. Alizarin Red S undergoes reversible redox reactions (for electrochemical detection) and irreversible chelation (for bone staining). Alizarin Red S is mainly used in bone metabolism research (labeling mineralized tissue), sugar detection (boric acid-sugar competition system) and metal ion sensing (such as zirconium ion detection)， and can be used in osteoporosis and metabolic disease research. | ||||||||||||||||||||
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Anthragallol | 99.55% | Anthragallol can insert base pairs of DNA. Anthragallol exhibits cytotoxicity by binding to DNA. | ||||||||||||||||||||
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Alizarin Red S | 95.0% | Alizarin Red S (ARS) is an anthraquinone derivative dye. When combined with cations such as calcium ions, the functional group of Alizarin Red S can form a coordination bond with the cation through the oxygen atom to show orange-red fluorescence. Alizarin Red S can be used for screening of calcium compounds in synovial fluid and detecting osteoblast differentiation, and can also be used for bone staining in mice. Excitation/emission wavelength: 500/570 nm. | ||||||||||||||||||||
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Lucidin ω-ethyl ether | Lucidin ω-ethyl ether (compound 17) is an anthraquinone metabolite isolated from the root part of Prismatomeris filamentosa with some antibacterial activity against Gram-positive and Gram-negative bacteria. | |||||||||||||||||||||
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Lucidin (Standard) | ≥98% | Lucidin (Standard) is the analytical standard of Lucidin. This product is intended for research and analytical applications. Lucidin (NSC 30546) is a natural component of madder and can induce mutations in bacterial and mammalian cells. | ||||||||||||||||||||
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Nuclear Fast Red | 97.62% | Nuclear Fast Red, an anthraquinone dye, is commonly used in conjunction with an excess of aluminum ions as a red nuclear counterstain. Nuclear fast red has been used as a histochemical and colorimetric reagent for calcium. Nuclear fast red as highly sensitive "off/on" fluorescent probe for detecting guanine. | ||||||||||||||||||||
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Rubiadin (Standard) | ≥98% | Rubiadin (Standard) is the analytical standard of Rubiadin (HY-N0444). This product is intended for research and analytical applications. Rubiadin is an orally active free radical scavenger that inhibits the activation of the NF-κB pathway. Rubiadin inhibits osteoclast formation, bone resorption, lipid peroxidation, HBV DNA replication and cancer cell proliferation; reduces pro-inflammatory cytokine levels; induces cancer cell apoptosis; and possesses antifungal, antimalarial, antibacterial and anticonvulsant activities. Rubiadin can be used in the research of osteoporosis, acute inflammation, chronic inflammation, carbon tetrachloride-induced liver injury, Alzheimer's disease, breast cancer, iron overload disorders, hepatitis B virus infection, colon cancer, liver cancer, T-lymphocytic leukemia, cervical cancer, diabetic nephropathy, epileptic seizures, fungal infections, malaria and bacterial infections. | ||||||||||||||||||||
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Alizarin | 99.48% | Alizarin is a natural dye. Alizarin can be extracted from the roots of madder plant. Alizarin activates AMPK and VEGFR2/eNOS pathway. Alizarin regulates PI3K/Akt and inhibits NF-κB pathway. Alizarin enhances CYP1A1 enzyme activity. Alizarin has protective effects on hypertension and vascular endothelial dysfunction. Alizarin has anti-tumor activity against multiple cancers including pancreatic cancer, breast cancer, osteosarcoma and liver cancer. Alizarin has been widely used as a pigment in textile fabrics and paintings. | ||||||||||||||||||||
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Lucidin-ω-Me ether | Lucidin-ω-Me ether (Compound 2) can be isolated from the roots of Knoxia valerianoides. Lucidin-ω-Me ether inhibits the advanced glycation end products (AGEs) formation in vitro(IC50: 62.79 μM). | |||||||||||||||||||||
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Anthraquinone-2-sulfonate sodium | Anthraquinone-2-sulfonate (sodium) is a microbial photosensitizer that exhibits capacitive property. | |||||||||||||||||||||
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Anthragallol-2-methyl ether | Anthragallol-2-methyl ether (compound 4) can be isolated from the fruits of Morinda citrifolia. | |||||||||||||||||||||
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References
- [1]. H Paul, et al. Alizarin red S staining as a screening test to detect calcium compounds in synovial fluid. Arthritis Rheum. 1983 Feb;26(2):191-200. [Content Brief]
- [2]. Soomin Lim, et al. Stimulatory Effects of KPR-A148 on Osteoblast Differentiation and Bone Regeneration. Tissue Eng Regen Med. 2019 Jul 17;16(4):405-413. [Content Brief]
- [3]. H Vilmann, et al. The in vivo staining of bone with alizarin red S. J Anat. 1969 Nov;105(Pt 3):533-45. [Content Brief]
- [4]. W Querido, et al. Giemsa as a fluorescent dye for mineralizing bone-like nodules in vitro. Biomed Mater. 2012 Feb;7(1):011001. [Content Brief]
- [5]. Bo Lai, et al. Application of excitation and emission matrix fluorescence (EEM) and UV-vis absorption to monitor the characteristics of Alizarin Red S (ARS) during electro-Fenton degradation process. Chemosphere.2013 Nov;93(11):2805-13. [Content Brief]
