1312345-89-3
1312345-89-3
Chemical Structure
GSK5750
- CAS No.: 1312345-89-3
- Formula:C16H12N4O2S
- Molecular Weight:324.36
IUPAC Name: 4-((benzo[b]thiophen-2-ylmethyl)amino)-1-hydroxypyrido[2,3-d]pyrimidin-2(1H)-one
InChIKey: JMKYKCCBXRBHQY-UHFFFAOYSA-N
SMILES: O=C1N(O)C2=NC=CC=C2C(NCC3=CC4=CC=CC=C4S3)=N1
Biological Activity: GSK5750 is a specific and potent HIV-1 reverse transcriptase ribonuclease H inhibitor with an IC50 value of 0.33 μM. GSK5750 is bound at the RNase H active site through a metalion chelation mechanism[1].
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GSK5750 | GSK5750 is a specific and potent HIV-1 reverse transcriptase ribonuclease H inhibitor with an IC50 value of 0.33 μM. GSK5750 is bound at the RNase H active site through a metalion chelation mechanism. | |||||||||||||||||||||
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References
Keywords
