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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
Methylated Derivative
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "Methylated Derivative" in MCE Product Catalog:
9
9 Cited Publications
Cat. No.: HY-19340
CAS No.: 24144-92-1
Synonyms: (E)-2,3',4,5'-tetramethoxystilbene
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TMS ((E)-2,3',4,5'-tetramethoxystilbene) is a selective and competitive CYP1B1 inhibitor with an IC50 of 6 nM and a Ki value of 3 nM. TMS shows a lesser extent inhibitory effect on CYP1A1 (IC50=300 nM) and CYP1A2 (IC50=3.1 μM). TMS is a methylated derivative of resveratrol and has anti-cancer activity .
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2 Cited Publications
DMU-212 is a methylated derivative of Resveratrol (HY-16561), with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2 protein. DMU-212 has orally active .
Cat. No.: HY-17442
CAS No.: 76801-85-9
Synonyms: Azaerythromycin A; Desmethyl Azithromycin
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Azathramycin (Azaerythromycin A) is a methylated derivative of the antibiotic Azithromycin (HY-17506).
Cat. No.: HY-16466
CAS No.: 391611-36-2
Spliceostatin A, the FR901464 (HY-16212) methylated derivative, is a potent anti-tumor agent. Spliceostatin A inhibits splicing and promotes pre-mRNA accumulation by binding SF3B1. SF3B1 is a subcomplex of U2 small nuclear ribonucleoprotein in the spliceosome. Spliceostatin A induces Apoptosis in chronic lymphocytic leukemia (CLL) cells .
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Meprednisone is a glucocorticoid and a methylated derivative of Prednisone (HY-B0214). Meprednisone modulates glucocorticoid receptor. Meprednisone is orally active .
Cat. No.: HY-W018326
CAS No.: 113942-30-6
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Temozolomide acid is a carboxylic acid derivative of Temozolomide (HY-17364) with anticancer activity. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide acid is promising for research of glioblastoma and brain cancer .
Cat. No.: HY-P4198
CAS No.: 2375600-56-7
Synonyms: Fmoc-Sar10
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DMF-DMA (N-Dimethoxymethyl-N,N-dimethylamine) is a reagent with both condensation and alkylation functions. DMF-DMA can undergo condensation reactions with active methylene groups or amino groups to generate enamine and imino derivatives, and can also act as an alkylating agent to methylate nitrogen and oxygen atoms in heterocyclic structures. DMF-DMA is widely used in the synthesis of enaminones and dimethylamino imine intermediates, as well as in the construction of heterocyclic backbones such as pyridine, pyrimidine and pyrazole. DMF-DMA can also serve as a polar aprotic co-solvent; although DMF-DMA cannot dissolve cellulose alone, it can form an efficient cellulose dissolution system with diallylimidazolium methoxyacetate .
Cat. No.: HY-W111226
CAS No.: 252049-16-4
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Cat. No.: HY-W012000
CAS No.: 52498-32-5
Synonyms: Boc-N-Me-Ile-OH
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Boc-N-methyl-L-isoleucine (Boc-N-Me-Ile-OH) is a Boc-protected N-methylated derivative of L-isoleucine (HY-N0771), as well as a protected amino acid building block .
Cat. No.: HY-W190923
CAS No.: 2353409-70-6
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MMAF-methyl ester is a methylated derivative of the tubulin inhibitor MMAF (HY-15579), and serves as a pharmaceutical intermediate for the development of antibody-drug conjugates (ADCs) and small-molecule drug conjugates (SMDCs) .
Cat. No.: HY-W010235
CAS No.: 4179-19-5
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Cat. No.: HY-W586822
CAS No.: 1352827-50-9
Synonyms: Pomalidomide-methyl
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N-methylated pomalidomide (Pomalidomide-methyl), a derivative of Pomalidomide (HY-10984), is a cereblon (CRBN) ligand. N-methylated pomalidomide is unable to recruit CRBN that can be used as a negative control for Pomalidomide. N-methylated pomalidomide can be used to synthesize PROTAC .
Cat. No.: HY-W010235R
CAS No.: 4179-19-5
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Cat. No.: HY-118728
CAS No.: 31753-19-2
Synonyms: PGA2 methyl ester
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Prostaglandin A2 methyl ester (PGA2 methyl ester) is a methylated derivative of the prostaglandin PGA2 (HY-113041) .
Cat. No.: HY-17442R
CAS No.: 76801-85-9
Synonyms: Azaerythromycin A (Standard); Desmethyl Azithromycin (Standard)
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Azathramycin (Azaerythromycin A) Standard is the analytical standard of Azathramycin (HY-17442). This product is intended for research and analytical applications. Azathramycin (Azaerythromycin A) is a methylated derivative of the antibiotic Azithromycin (HY-17506) .
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Meprednisone (Standard) is the analytical standard of Meprednisone. This product is intended for research and analytical applications. Meprednisone is a glucocorticoid and a methylated derivative of Prednisone (HY-B0214). Meprednisone modulates glucocorticoid receptor. Meprednisone is orally active .
Cat. No.: HY-P5515
CAS No.: 409085-40-1
Cat. No.: HY-172002
CAS No.: 98923-57-0
Synonyms: 3'-O-Methyl GTP sodium
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3'-O-Methylguanosine-5'-O-triphosphate (3'-O-Methyl GTP) sodium is a methylated derivative of Guanosine 5'-triphosphate (HY-W010737). 3'-O-Methylguanosine-5'-O-triphosphate has been used as a chain termination reagent in the preparation of early RNA polymerase II elongation intermediates.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
