Fmoc-N(Me)-Sar10
Based on 1 Customer Validation
Fmoc-N(Me)-Sar10 (Fmoc-Sar10) is an Fmoc-protected derivative of a methylated sarcosine decamer, which supports cell adhesion, proliferation, and maintenance of cell phenotype. Fmoc-N(Me)-Sar10 is primarily used in peptide synthesis to introduce enzymatically stable spacer sequences. By mimicking the extracellular matrix (ECM), Fmoc-N(Me)-Sar10 provides a 3D growth microenvironment for cells and is mainly used in tissue engineering and 3D cell culture, particularly suitable for in vitro culture studies of cells such as chondrocytes.
For research use only. We do not sell to patients.
- Purity: 98.22%
- CAS No.: 2375600-56-7
- Formula: C45H62N10O13
- Molecular Weight:951.03
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Fmoc-N(Me)-Sar10 is primarily used as a building block in the synthesis of peptide ligand-conjugates, for introducing N-methylated sarcosine repeat sequences to enhance the enzymatic stability of target peptides, alter conformational flexibility, or act as a spacer to connect bioactive peptides with functional reagents (such as fluorescent probes, radiolabels, and drug molecules)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2375600-56-7
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Appearance Solid
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Molecular Weight 951.03
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Formula C45H62N10O13
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Color White to off-white
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Synonyms
Fmoc-Sar10
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (105.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0515 mL | 5.2575 mL | 10.5149 mL | 26.2873 mL |
| 5 mM | 0.2103 mL | 1.0515 mL | 2.1030 mL | 5.2575 mL | |
| 10 mM | 0.1051 mL | 0.5257 mL | 1.0515 mL | 2.6287 mL | |
| 15 mM | 0.0701 mL | 0.3505 mL | 0.7010 mL | 1.7525 mL | |
| 20 mM | 0.0526 mL | 0.2629 mL | 0.5257 mL | 1.3144 mL | |
| 25 mM | 0.0421 mL | 0.2103 mL | 0.4206 mL | 1.0515 mL | |
| 30 mM | 0.0350 mL | 0.1752 mL | 0.3505 mL | 0.8762 mL | |
| 40 mM | 0.0263 mL | 0.1314 mL | 0.2629 mL | 0.6572 mL | |
| 50 mM | 0.0210 mL | 0.1051 mL | 0.2103 mL | 0.5257 mL | |
| 60 mM | 0.0175 mL | 0.0876 mL | 0.1752 mL | 0.4381 mL | |
| 80 mM | 0.0131 mL | 0.0657 mL | 0.1314 mL | 0.3286 mL | |
| 100 mM | 0.0105 mL | 0.0526 mL | 0.1051 mL | 0.2629 mL |