134029-62-2
134029-62-2
Chemical Structure
DMU-212
- CAS No.: 134029-62-2
- Formula:C18H20O4
- Molecular Weight:300.35
IUPAC Name: (E)-1,2,3-trimethoxy-5-(4-methoxystyryl)benzene
InChIKey: GGFQQRXTLIJXNY-AATRIKPKSA-N
SMILES: COC1=CC=C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)C=C1
Biological Activity: DMU-212 is a methylated derivative of Resveratrol (HY-16561), with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2 protein. DMU-212 has orally active[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DMU-212 | 99.31% | DMU-212 is a methylated derivative of Resveratrol (HY-16561), with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2 protein. DMU-212 has orally active. | ||||||||||||||||||||
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References
- [1]. Vasilis Pericles Androutsopoulos, et al. Activation of ERK1/2 is required for the antimitotic activity of the resveratrol analogue 3,4,5,4'-tetramethoxystilbene (DMU-212) in human melanoma cells. Exp Dermatol. 2015 Aug;24(8):632-4. [Content Brief]
- [2]. Hanna Piotrowska, et al. DMU-212 inhibits tumor growth in xenograft model of human ovarian cancer. Biomed Pharmacother. 2014 May;68(4):397-400. [Content Brief]
Keywords
