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Cat. No.: HY-117867A

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AVE-8063 hydrochloride

(Synonyms: AC-7739)

AVE-8063 (AC-7739) hydrochloride is a therapeutic agent associated with the modulation of inflammatory responses in inflammatory bowel disease (IBD), displaying mechanisms that may be relevant for precision targeting in current therapies.

For research use only. We do not sell to patients.

CAS No.: 162705-22-8
Formula: C₁₈H₂₂ClNO₄
Molecular Weight:351.82

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

AVE-8063 hydrochloride Chemical Structure

CAS No.: 162705-22-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
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Classifications
Bioz

Biological Activity

Description

All Endogenous Metabolite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Colon 26	IC₅₀	2.8 nM Compound: 4	In vitro cytotoxicity against colon 26 adenocarcinoma cell line was evaluated. In vitro cytotoxicity against colon 26 adenocarcinoma cell line was evaluated.	[PMID: 9873694]
Colon 26	IC₅₀	2.8 nM Compound: 5	Cytotoxic activity was determined against Colon 26 adenocarcinoma cells Cytotoxic activity was determined against Colon 26 adenocarcinoma cells	[PMID: 9873736]

Chemical Information

CAS No. 162705-22-8
Molecular Weight 351.82
Formula C₁₈H₂₂ClNO₄
SMILES

COC1=C(C=C(C=C1OC)/C=C\C2=CC(N)=C(C=C2)OC)OC.Cl
Synonyms

AC-7739
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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AVE-8063 hydrochloride

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

AVE-8063 hydrochloride Related Classifications

HY-117867A Related Classifications