1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. AVE-8063 hydrochloride

AVE-8063 (AC-7739) hydrochloride is a therapeutic agent associated with the modulation of inflammatory responses in inflammatory bowel disease (IBD), displaying mechanisms that may be relevant for precision targeting in current therapies.

For research use only. We do not sell to patients.

AVE-8063 hydrochloride

AVE-8063 hydrochloride Chemical Structure

CAS No. : 162705-22-8

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Based on 1 publication(s) in Google Scholar

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Description

AVE-8063 (AC-7739) hydrochloride is a therapeutic agent associated with the modulation of inflammatory responses in inflammatory bowel disease (IBD), displaying mechanisms that may be relevant for precision targeting in current therapies.

Cellular Effect
Cell Line Type Value Description References
Colon 26 IC50
2.8 nM
Compound: 4
In vitro cytotoxicity against colon 26 adenocarcinoma cell line was evaluated.
In vitro cytotoxicity against colon 26 adenocarcinoma cell line was evaluated.
[PMID: 9873694]
Colon 26 IC50
2.8 nM
Compound: 5
Cytotoxic activity was determined against Colon 26 adenocarcinoma cells
Cytotoxic activity was determined against Colon 26 adenocarcinoma cells
[PMID: 9873736]
Molecular Weight

351.82

Formula

C18H22ClNO4

CAS No.
SMILES

COC1=C(C=C(C=C1OC)/C=C\C2=CC(N)=C(C=C2)OC)OC.Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
AVE-8063 hydrochloride
Cat. No.:
HY-117867A
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