20 Results for "

Methyldopa hydrate

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "Methyldopa hydrate" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-B0225
CAS No.: 555-30-6
Synonyms: L-(-)-α-Methyldopa; MK-351
Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system .
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2
2 Cited Publications
Cat. No.: HY-B0225B
CAS No.: 41372-08-1
Synonyms: L-(-)-α-Methyldopa hydrate; MK-351 hydrate
Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system .
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1
1 Cited Publications
Cat. No.: HY-113468A
CAS No.: 300-48-1
Purity:  99.16%
Synonyms: 3-Methoxy-L-tyrosine; 3-O-Methyl-L-DOPA
3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA (HY-N0304) that can cross the blood-brain barrier (BBB). 3-O-Methyldopa inhibits the astrocyte-mediated protective effect of L-DOPA (HY-N0304) on dopaminergic neurons. In addition, 3-O-Methyldopa has certain antidepressant and neuroprotective activities. 3-O-Methyldopa can be used in the research of nervous system diseases such as depression and Parkinson's disease .
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Cat. No.: HY-113468AS
CAS No.: 586954-09-8
Purity:  ≥99.0%
Synonyms: 3-Methoxy-L-tyrosine-d3; 3-O-Methyl-L-DOPA-d3
3-O-Methyldopa-d3 (3-Methoxy-L-tyrosine-d3) is deuterium labeled 3-O-Methyldopa (HY-113468A). 3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA (HY-N0304) that can cross the blood-brain barrier (BBB). 3-O-Methyldopa inhibits the astrocyte-mediated protective effect of L-DOPA (HY-N0304) on dopaminergic neurons. In addition, 3-O-Methyldopa has certain antidepressant and neuroprotective activities. 3-O-Methyldopa can be used in the research of nervous system diseases such as depression and Parkinson's disease .
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Cat. No.: HY-107915
CAS No.: 829-74-3
Purity:  98.35%
Synonyms: (-)-Cobefrin; (-)-α-Methylnoradrenaline; (-)-Nordefrin
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Levonordefrin ((-)-Cobefrin; (-)-α-Methylnoradrenaline; (-)-Nordefrin) is an α-adrenergic receptor agonist with blood pressure regulatory properties. Levonordefrin is a key metabolite responsible for the hypotensive effect of α-methyldopa. By stimulating central α-adrenergic receptors in the nucleus tractus solitarius region of the medulla oblongata, Levonordefrin induces centrally mediated hypotension and bradycardia. When administered intravenously, Levonordefrin increases mean arterial blood pressure in a dose-dependent manner. Levonordefrin is applicable for research on the pathophysiology of hypertension and drug metabolism .
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Cat. No.: HY-B1696
CAS No.: 6014-30-8
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Methyldopate is an ethyl ester proagent of α-Methyldopa (α-MD; HY-B0225). Methyldopa (L-(-)-α-Methyldopa) is an α-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopate has the potential for severe hypertension research .
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Cat. No.: HY-121809S
Purity:  98.17%
DL-Methyldopa-d3 is deuterium labeled DL-Methyldopa.
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Cat. No.: HY-113468AR
CAS No.: 300-48-1
Synonyms: 3-Methoxy-L-tyrosine (Standard); 3-O-Methyl-L-DOPA (Standard)
3-O-Methyldopa (Standard) is the analytical standard of 3-O-Methyldopa. This product is intended for research and analytical applications. 3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine .
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Cat. No.: HY-W012264
CAS No.: 200630-46-2
Synonyms: 3-Methoxy-L-tyrosine monohydrate; 3-O-Methyl-L-DOPA monohydrate
Target:  

COMT

Research Areas:  

Neurological Disease

3-O-Methyldopa monohydrate (3-Methoxy-L-tyrosine monohydrate) is a significant metabolite of L-DOPA produced through the action of catechol O-methyltransferase (COMT). Unlike its precursor, 3-O-Methyldopa does not serve as a substrate or inhibitor of L-amino acid decarboxylase activity. Additionally, the inhibition of COMT can amplify the anti-Parkinson effects of L-DOPA.
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Cat. No.: HY-B0225A
CAS No.: 884-39-9
Synonyms: L-(-)-α-Methyldopa hydrochloride; MK-351 hydrochloride
Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system .
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Cat. No.: HY-B1696A
CAS No.: 2508-79-4
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Methyldopate hydrochloride is an ethyl ester hydrochloride proagent of α-Methyldopa (α-MD; HY-B0225). Methyldopa (L-(-)-α-Methyldopa) is an α-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopate hydrochloride has the potential for severe hypertension research .
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Cat. No.: HY-W401531S
CAS No.: 1259947-39-1
(R)-3-O-Methyldopa-d3 is a deuterium labeled (R)-3-O-Methyldopa, and (R)-3-O-Methyldopa is an R-enantiomer of 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of L-DOPA and dopamine .
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Cat. No.: HY-W401531S1
CAS No.: 2714485-35-3
(R)-3-O-Methyldopa-d3 (hydrochloride) is a deuterium labeled (R)-3-O-Methyldopa, and (R)-3-O-Methyldopa is an R-enantiomer of 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of L-DOPA and dopamine .
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Cat. No.: HY-B0225BR
CAS No.: 41372-08-1
Synonyms: L-(-)-α-Methyldopa hydrate (Standard); MK-351 hydrate (Standard)
Methyldopa (hydrate) (Standard) is the analytical standard of Methyldopa (hydrate). This product is intended for research and analytical applications. Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system .
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Cat. No.: HY-B0225AS
Synonyms: L-(-)-α-Methyldopa-d3 hydrochloride; MK-351-d3 hydrochloride
Methyldopa-d3 (hydrochloride) is deuterium labeled Methyldopa (hydrochloride). Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system .
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Cat. No.: HY-Z0792S
CAS No.: 586954-11-2
4-O-Methyldopa-d3 is deuterium labeled 4-O-Methyldopamine.
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Cat. No.: HY-113468AS1
Synonyms: 3-Methoxy-L-tyrosine-d3 hydrate; 3-O-Methyl-L-DOPA-d3 hydrate
3-O-Methyldopa-d3 (hydrate) is the deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa (3-Methoxy-L-tyrosine) hydrate is a metabolite of L-DOPA (HY-N0304) that can cross the blood-brain barrier (BBB). 3-O-Methyldopa hydrate inhibits the astrocyte-mediated protective effect of L-DOPA (HY-N0304) on dopaminergic neurons. In addition, 3-O-Methyldopa hydrate has certain antidepressant and neuroprotective activities. 3-O-Methyldopa hydrate can be used in the research of nervous system diseases such as depression and Parkinson's disease .
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Cat. No.: HY-CE01703
Synonyms: Methyldopa-coenzyme A
Research Areas:  

Metabolic Disease

Methyldopa-CoA (Methyldopa-coenzyme A) is a coenzyme A derivative .
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Cat. No.: HY-107915R
CAS No.: 829-74-3
Synonyms: (-)-Cobefrin (Standard); (-)-α-Methylnoradrenaline (Standard); (-)-Nordefrin (Standard)
Research Areas:  

Others

Levonordefrin (Standard) is the analytical standard of Levonordefrin. This product is intended for research and analytical applications. Levonordefrin ((-)-Cobefrin; (-)-α-Methylnoradrenaline; (-)-Nordefrin) is an α-adrenergic receptor agonist with blood pressure regulatory properties. Levonordefrin is a key metabolite responsible for the hypotensive effect of α-methyldopa. By stimulating central α-adrenergic receptors in the nucleus tractus solitarius region of the medulla oblongata, Levonordefrin induces centrally mediated hypotension and bradycardia. When administered intravenously, Levonordefrin increases mean arterial blood pressure in a dose-dependent manner. Levonordefrin is applicable for research on the pathophysiology of hypertension and drug metabolism .
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Cat. No.: HY-121809
CAS No.: 55-40-3
Synonyms: rac α-Methyl DOPA
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

DL-Methyldopa (rac α-Methyl DOPA) (Compound 14) is a centrally acting α2-adrenergic receptor agonist. DL-Methyldopa can serve as an intermediate in neurotransmitter biosynthesis. DL-Methyldopa can be used in research on neurological diseases .
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