41372-08-1
41372-08-1
Chemical Structure
Methyldopa hydrate
Synonym(s): L-(-)-α-Methyldopa hydrate; MK-351 hydrate
- CAS No.: 41372-08-1
- Formula:C10H16NO5.5
- Molecular Weight:238.24
SMILES: OC1=C(O)C=CC(C[C@@](C)(C(O)=O)N)=C1.O
Biological Activity: Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system[1][2].
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Methyldopa hydrate | 99.95% | Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system. | ||||||||||||||||||||
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Methyldopa hydrate (Standard) | ≥98% | Methyldopa (hydrate) (Standard) is the analytical standard of Methyldopa (hydrate). This product is intended for research and analytical applications. Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.97
HY-B0225AMethyldopa hydrochloride -
Similarity Score 0.85
HY-B0311ACarbidopa monohydrate -
Similarity Score 0.85
HY-B0311RCarbidopa (Standard) -
Similarity Score 0.84
HY-B0311DCarbidopa hydrochloride -
Similarity Score 0.83
HY-B1696Methyldopate -
Similarity Score 0.82
HY-B1696AMethyldopate hydrochloride -
Similarity Score 0.76
HY-W011963Melevodopa hydrochloride -
Similarity Score 0.74
HY-116016Etilevodopa -
Similarity Score 0.74
HY-116016AEtilevodopa hydrochloride -
Explore the MedChemAI to find more analogs
References
- [1]. Sweet CS. New centrally acting antihypertensive drugs related to methyldopa and clonidine. Hypertension. 1984;6(5 Pt 2):II51-II56. [Content Brief]
- [2]. Fox GR, et al. The effects of phenobarbital, atropine, L-alpha-methyldopa, and DL-propranolol on dieldrin-induced hyperglycemia in the adult rat. Toxicol Appl Pharmacol. 1985;78(3):342-350. [Content Brief]
