1. Neuronal Signaling
    GPCR/G Protein
    Metabolic Enzyme/Protease
  2. Dopamine Receptor
    Drug Metabolite
  3. Etilevodopa

Etilevodopa (Synonyms: L-DOPA ethyl ester; Levodopa ethyl ester)

Cat. No.: HY-116016
Handling Instructions

Etilevodopa (L-Dopa ethyl ester), an ethyl-ester prodrug of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa is used for the treatment of Parkinson disease (PD). Levodopa is the direct precursor of dopamine and is a suitable prodrug as it facilitates CNS penetration and delivers dopamine.

For research use only. We do not sell to patients.

Etilevodopa Chemical Structure

Etilevodopa Chemical Structure

CAS No. : 37178-37-3

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10 mM * 1 mL in DMSO USD 334 Ask For Quote & Lead Time
Solid
5 mg USD 400 Ask For Quote & Lead Time
10 mg USD 670 Ask For Quote & Lead Time

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Description

Etilevodopa (L-Dopa ethyl ester), an ethyl-ester prodrug of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa is used for the treatment of Parkinson disease (PD). Levodopa is the direct precursor of dopamine and is a suitable prodrug as it facilitates CNS penetration and delivers dopamine[1][2][3].

In Vitro

Etilevodopa (L-Dopa ethyl ester) passes unchanged through the stomach to the duodenum, where it is rapidly hydrolyzed by local esterases to Levodopa and ethanol, and is subsequently absorbed into the blood stream as Levodopa[1].
Compared with standard Levodopa, Etilevodopa has greater solubility in the stomach, faster passage to the small intestine, and a shortened time to maximum Levodopa concentration[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

225.24

Formula

C11H15NO4

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References

Purity: ≥97.0%

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Etilevodopa
Cat. No.:
HY-116016
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