4 Results for "

N-degron pathway

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "N-degron pathway" in MCE Product Catalog:

Cat. No.: HY-P5559
CAS No.: 2582803-80-1
Target:  

PROTACs

Research Areas:  

Cancer

ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research .
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Cat. No.: HY-180959
CAS No.: 3031840-37-3
Research Areas:  

Cancer

NEP168 is an ERα PROTAC degrader designed based on the GID4 E3 ligase. NEP168 can be used for the study of breast cancer .
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Cat. No.: HY-180960
CAS No.: 3031840-41-9
Target:  

PROTACs SWI/SNF Complex

Research Areas:  

Cancer

NEP202 is a SMARCA2 PROTAC degrader designed based on the GID4 E3 ligase. NEP168 can be used for cancer research .
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Cat. No.: HY-181000
CAS No.: 3074520-74-1
Research Areas:  

Cancer

PROTAC PLK1 Degrader-3 (Compound DD-1) is a PLK1 PROTAC degrader based on the N-deglycosylation pathway, with a Kd value of 2.2 μM. The cell penetration ability of PROTAC PLK1 Degrader-3 is limited and a higher concentration is required to achieve significant degradation effects. PROTAC PLK1 Degrader-3 can be used for research on non-small cell lung cancer .
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