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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
NCS
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "NCS" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-N2037C
CAS No.: 105990-27-0
Synonyms: (S)-Norcoclaurine hydrobromide
Category:
Alkaloids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields Isoquinoline Alkaloids
Target:
1
1 Cited Publications
Cat. No.: HY-W008645
CAS No.: 131733-92-1
Target:
Research Areas:
NCS-382 (sodium) is a potent GABA receptor antagonist. NCS-382 (sodium) has anti-sedative and anti-hypnotic activities and can be used in research related to neurological diseases .
Cat. No.: HY-159181
CAS No.: 2194580-71-5
Cat. No.: HY-W012653
CAS No.: 122-00-9
Target:
Target:
Research Areas:
IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex. IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently .
Cat. No.: HY-159180
CAS No.: 1660127-21-8
Cat. No.: HY-164576
CAS No.: 1374994-81-6
Synonyms: NODA-Bz-SCN
Research Areas:
NCS-MP-NODA (NODA-Bz-SCN) is a NODA-derived bifunctional chelator. NCS-MP-NODA can conjugate with biomolecules including the RGD tripeptide, and is used for aluminum-[ 18F] fluoride-based positron emission tomography (PET) radiolabeling. NCS-MP-NODA can conjugate with the free lysine amino group of the PD-L1-specific peptide DK221 to generate DK222, which can be radiolabeled with 18F to form [ 18F]DK222. NCS-MP-NODA can be used in studies related to triple-negative breast cancer, melanoma and colon cancer .
Cat. No.: HY-N2037B
CAS No.: 22672-77-1
Synonyms: (S)-Norcoclaurine
Category:
Alkaloids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields Isoquinoline Alkaloids
Target:
Cat. No.: HY-101207
CAS No.: 520505-01-5
Target:
Research Areas:
NCS-382 is a potent GABA receptor antagonist and also a GHBR receptor antagonist. NCS-382 has anticonvulsant and antisedative activity. NCS-382 is used in the related research of hereditary nervous system diseases .
Cat. No.: HY-159183
CAS No.: 1807847-98-8
Cat. No.: HY-138269
CAS No.: 157380-45-5
Synonyms: CHX-A''-DTPA-NCS
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Research Areas:
Barzuxetan can be used for cancer diseases research .
Cat. No.: HY-121503
CAS No.: 68207-21-6
Target:
Research Areas:
FD44 is a phenothiazine small molecule that inhibits the interaction between neuronal calcium sensor 1 (NCS-1) and the guanine exchange factor Ric8a, a key regulator of synapse number and neurotransmitter release probability. In the Drosophila genetic autism model of fragile X syndrome (FXS), FD44 restored normal synapse number and associative learning .
Cat. No.: HY-RS09102
Target:
Research Areas:
NCS1 Human Pre-designed siRNA Set A contains three designed siRNAs for NCS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-13726
CAS No.: 91441-23-5
Synonyms: Oxantrazole; NCS 349174
Target:
Research Areas:
Piroxantrone (Oxantrazole) is a potent DNA topoisomerase II-targeting anthrapyrazole antitumor agent. Piroxantrone displays cardiotoxicity .
Cat. No.: HY-138269A
Synonyms: CHX-A''-DTPA-NCS hydrochloride
Cat. No.: HY-W705415A
CAS No.: 3423-07-2
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Research Areas:
(S)-N-methylcoclaurine is a substrate of CyNMCH. (S)-N-methylcoclaurine serves as an important branch point intermediate in benzylisoquinoline alkaloid biosynthesis.
Cat. No.: HY-135034
CAS No.: 581099-89-0
Target:
Research Areas:
UMB68 sodium is a selective GHB receptor ligand. UMB68 sodium displaces [ 3H]NCS-382 with an IC50 of 38 nM in rat cerebrocortical membranes. UMB68 sodium has no significant affinity at GABAB receptors, cannot be metabolized to GABA-active compounds .
Cat. No.: HY-W012653R
CAS No.: 122-00-9
Cat. No.: HY-W012653S
CAS No.: 358730-83-3
Cat. No.: HY-W416153
CAS No.: 91294-63-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
