1 Result for "

NVP-DKY709

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NVP-DKY709" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-144998
CAS No.: 2291360-73-9
Purity:  98.86%
Research Areas:  

Inflammation/Immunology Cancer

NVP-DKY709 is an orally active and selective IKZF2 molecular glue degrader with the Dmax and DC50 of 53% and 4 nM, respectively. In addition, NVP-DKY709 can degrade IKZF4 (DC50: 13 nM) and SALL4 (DC50: 2 nM). NVP-DKY709 exerts anti-tumor activity by binding with CRBN to change conformation and recruit and degrade IKZF2 .
loading...
    loading...