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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
150 Results for "
Nucleoside Metabolite
" in MedChemExpress (MCE) Product Catalog:
Products (150)
150 Results for "Nucleoside Metabolite" in MCE Product Catalog:
16
3
3 Cited Publications
Cat. No.: HY-44358
CAS No.: 1911578-74-9
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Remdesivir nucleoside monophosphate is a metabolite of Remdesivir (HY-104077) .
3
3 Cited Publications
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GS-704277 is an alanine metabolite of Remdesivir (HY-104077). GS-704277 is further hydrolyzed to GA-441524 (HY-103586) with antiviral activity. Remdesivir, a nucleoside analogue with effective antiviral activity, is highly effective in the control of SARS-CoV-2 (COVID-19) infection .
2
2 Cited Publications
2
2 Cited Publications
Cat. No.: HY-122524A
CAS No.: 81100-62-1
Research Areas:
7-Methylguanosine iodide is an iodide of 7-Methylguanosine (HY-122524). 7-Methylguanosine is a modified nucleoside widely present in various RNAs and a key metabolite of the 5'-cap structure of eukaryotic mRNA. 7-Methylguanosine plays important roles in stabilizing RNA structures, regulating translation, and other aspects .
2
Elsulfavirine (R-1206) is an orally active human carbonic anhydrase (carbonic anhydrase, CA) inhibitor and an allosteric inhibitor of HIV-1 non-nucleoside reverse transcriptase (NNRT). Elsulfavirine also targets and blocks the interaction between adenylosuccinate lyase (ADSL) and insulin-induced gene proteins INSIG1/2, blocks SREBP-1-mediated de novo lipid synthesis, and inhibits the proliferation of liver cancer cells. The combination of Elsulfavirine and Lenvatinib (HY-10981) produces a synergistic anti-tumor effect. Elsulfavirine is converted into the active metabolite VM1500A in vivo, blocks the DNA polymerase activity of reverse transcriptase, and inhibits HIV-1 replication. Elsulfavirine exhibits a Ki of 1960 nM-52400 nM against human carbonic anhydrase isoforms including I, VII, VI, VA, VB, IX, XIII, XIV. Elsulfavirine is used in studies related to HIV-1 infection and liver cancer .
1
1 Cited Publications
Cat. No.: HY-W019670
CAS No.: 3768-18-1
Cat. No.: HY-17026E
Synonyms: dFdCTP trisodium
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6-Thioguanosine (6-Mercaptoguanosine), an active nucleoside, is an Azathioprine metabolite. 6-Thioguanosine has immunosuppressive effects .
Cat. No.: HY-154945
CAS No.: 17388-80-6
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N-(5-Amino-1-ribosyl-4-imidazolecarbonyl)-L-aspartic acid is a nucleoside metabolite .
Cat. No.: HY-W702789
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N-(5-Amino-1-ribosyl-4-imidazolecarbonyl)-L-aspartic acid disodium is a nucleoside metabolite .
Cat. No.: HY-W104462
CAS No.: 4228-66-4
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Cat. No.: HY-167467
CAS No.: 15357-34-3
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Cat. No.: HY-W725130
CAS No.: 1912-55-6
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Cat. No.: HY-180623
CAS No.: 106843-82-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
