20244-86-4
20244-86-4
Chemical Structure
7-Methylguanosine
- CAS No.: 20244-86-4
- Formula:C11H16N5O5+
- Molecular Weight:298.27
IUPAC Name: 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7-methyl-9H-purin-7-ium-6-olate
InChIKey: OGHAROSJZRTIOK-KQYNXXCUSA-N
SMILES: O=C1C2=C(N([C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C=[N+]2C)NC(N)=N1
Biological Activity: 7-Methylguanosine is a modified nucleoside widely present in various RNAs and a key metabolite of the 5'-cap structure of eukaryotic mRNA. 7-Methylguanosine plays important roles in stabilizing RNA structures, regulating translation, and other aspects[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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7-Methylguanosine | 99.10% | 7-Methylguanosine is a modified nucleoside widely present in various RNAs and a key metabolite of the 5'-cap structure of eukaryotic mRNA. 7-Methylguanosine plays important roles in stabilizing RNA structures, regulating translation, and other aspects. | ||||||||||||||||||||
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7-Methylguanosine-d3 | 98.54% | 7-Methylguanosine-d3 is the deuterium labeled 7-Methylguanosine. 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8 ± 7.5 μM. | ||||||||||||||||||||
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References
- [1]. Tomikawa C. 7-Methylguanosine Modifications in Transfer RNA (tRNA). Int J Mol Sci. 2018 Dec 17;19(12):4080. [Content Brief]
- [2]. Kozarski M, et al. 7-Methylguanosine monophosphate analogues with 5'-(1,2,3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase. Bioorg Med Chem. 2018 Jan 1;26(1):191-199. [Content Brief]
