1. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  2. Nucleoside Antimetabolite/Analog Endogenous Metabolite
  3. 7-Methylguanosine-d3

7-Methylguanosine-d3 is the deuterium labeled 7-Methylguanosine[1]. 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8 ± 7.5 μM[2].

For research use only. We do not sell to patients.

7-Methylguanosine-d<sub>3</sub> Chemical Structure

7-Methylguanosine-d3 Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Description

7-Methylguanosine-d3 is the deuterium labeled 7-Methylguanosine[1]. 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8 ± 7.5 μM[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

301.29

Formula

C11H13D3N5O5

Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3[N](C([2H])([2H])[2H])=C2)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
7-Methylguanosine-d3
Cat. No.:
HY-122524S
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