1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. GS-704277

GS-704277 

Cat. No.: HY-136303 Purity: 96.25%
COA Handling Instructions

GS-704277 is an alanine metabolite of Remdesivir. Remdesivir, a nucleoside analogue with effective antiviral activity, is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro.

For research use only. We do not sell to patients.

GS-704277 Chemical Structure

GS-704277 Chemical Structure

CAS No. : 1911579-04-8

Size Price Stock Quantity
1 mg USD 500 In-stock
Estimated Time of Arrival: December 31
5 mg USD 1300 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1850 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

GS-704277 is an alanine metabolite of Remdesivir. Remdesivir, a nucleoside analogue with effective antiviral activity, is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].

Molecular Weight

442.32

Appearance

Solid

Formula

C15H19N6O8P

CAS No.
SMILES

OC([[email protected]](C)NP(OC[[email protected]@H]1[[email protected]@H](O)[[email protected]@H](O)[[email protected]@](C2=CC=C3N2N=CN=C3N)(C#N)O1)(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 2.17 mg/mL (4.91 mM; ultrasonic and warming and heat to 60°C)

DMSO : 2 mg/mL (4.52 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2608 mL 11.3040 mL 22.6081 mL
5 mM --- --- ---
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2

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Product Name:
GS-704277
Cat. No.:
HY-136303
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