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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
Nucleoside hydrolase
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "Nucleoside hydrolase" in MCE Product Catalog:
7
7 Cited Publications
Research Areas:
Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM) . Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research .
Cat. No.: HY-W040329
CAS No.: 958-09-8
Cat. No.: HY-W011683
CAS No.: 16373-93-6
Target:
Research Areas:
Nucleoside hydrolase (IAGNH) is a glycosidase. Nucleoside hydrolase (IAGNH) catalyzes the cleavage of the N-glycosidic bond in nucleosides to enable the recycling of the nucleobases and Rib .
Cat. No.: HY-W040329R
CAS No.: 958-09-8
Cat. No.: HY-W040329S1
Cat. No.: HY-W011683S6
CAS No.: 2483830-27-7
Cat. No.: HY-W011683S
CAS No.: 446276-63-7
Cat. No.: HY-W011683S3
CAS No.: 478510-77-9
Cat. No.: HY-179249
Research Areas:
Fluoroneplanocin A-8N (Compound 3a) is an inhibitor targeting SAH hydrolase (IC50 = 1.51 μM) and viral RNA polymerase. Fluoroneplanocin A-8N exhibits broad-spectrum anti-SARS-CoV-2 and dengue virus activity, with EC50 values of 12.2 and 37.4 μM respectively. Fluoroneplanocin A-8N has no cytotoxicity. Fluoroneplanocin A-8N can be used for anti-positive-strand viruses .
Cat. No.: HY-117831
CAS No.: 19056-78-1
Target:
Research Areas:
NSC-79887 is a nucleoside hydrolase (NH) inhibitor with activity against Bacillus anthracis. NSC-79887 is considered a good candidate inhibitor of nucleoside hydrolases for biological testing and further development. The pharmacokinetic (ADMET) prediction of NSC-79887 showed that all physicochemical parameters were within the acceptable range for human use .
Cat. No.: HY-170963
LASSBio-1985 is an NHLd inhibitor (nucleoside hydrolase from Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. LASSBio-1985 exhibits selective toxicity against Leishmania parasites, with no toxicity to mammalian cells, making it a promising candidate for research in the field of anti-infective therapies .
Cat. No.: HY-123055R
CAS No.: 34240-05-6
Target:
Reference Standards Nucleoside Antimetabolite/Analog S-adenosylhomocysteine hydrolase (SAHH)
Research Areas:
Adenosine dialdehyde (Standard) is the analytical standard of Adenosine dialdehyde. This product is intended for research and analytical applications. Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM) . Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research .
Cat. No.: HY-W778207
CAS No.: 478510-79-1
Cat. No.: HY-W011683R
CAS No.: 16373-93-6
Category:
Cat. No.: HY-W011683S1
Cat. No.: HY-W011683S7
Cat. No.: HY-W745905
CAS No.: 106568-85-8
Cat. No.: HY-W011683S2
Cat. No.: HY-W040329S
CAS No.: 1987883-24-8
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
