Fluoroneplanocin A-8N
Fluoroneplanocin A-8N (Compound 3a) is an inhibitor targeting SAH hydrolase (IC50 = 1.51 μM) and viral RNA polymerase. Fluoroneplanocin A-8N exhibits broad-spectrum anti-SARS-CoV-2 and dengue virus activity, with EC50 values of 12.2 and 37.4 μM respectively. Fluoroneplanocin A-8N has no cytotoxicity. Fluoroneplanocin A-8N can be used for anti-positive-strand viruses.
For research use only. We do not sell to patients.
- Formula: C10H11FN6O3
- Molecular Weight:282.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
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RNA Polymerase |
Chemical Information
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Molecular Weight 282.23
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Formula C10H11FN6O3
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SMILES
O[C@@H]1[C@H](O)C(CO)=C(F)[C@H]1N2N=NC3=C(N)N=CN=C32
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Fluoroneplanocin A-8N Related Classifications
HY-179249 Related Classifications
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- Fluoroneplanocin A-8N
- DNA/RNA Synthesis
- Nucleoside Antimetabolite/Analog
- SARS-CoV
- Dengue Virus
- 8-Aza Fluoroneplanocin
- SAH hydrolase inhibitor
- RNA-dependent RNA polymerase
- broad-spectrum antiviral
- SARS-CoV-2
- Dengue virus
- dual-targeting mechanism
- nucleoside analog
- cytotoxicity reduction
- structure-activity relationship
- Inhibitor
- inhibitor
- inhibit