34240-05-6
34240-05-6
Chemical Structure
Adenosine dialdehyde
- CAS No.: 34240-05-6
- Formula:C10H11N5O4
- Molecular Weight:265.23
IUPAC Name: 2-(1-(6-amino-9H-purin-9-yl)-2-oxoethoxy)-3-hydroxypropanal
InChIKey: ILMNSCQOSGKTNZ-UHFFFAOYSA-N
SMILES: O=CC(OC(C=O)CO)N1C=NC2=C(N)N=CN=C12
Biological Activity: Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM)[1]. Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research[1][2].
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Adenosine dialdehyde | 99.0% | Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research. | ||||||||||||||||||||
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Adenosine dialdehyde (Standard) | ≥98% | Adenosine dialdehyde (Standard) is the analytical standard of Adenosine dialdehyde. This product is intended for research and analytical applications. Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research. | ||||||||||||||||||||
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References
- [1]. V Ramakrishnan, et al. Adenosine dialdehyde and neplanocin A: Potent inhibitors of S-adenosylhomocysteine hydrolase in neuroblastoma N2a cells. Neurochem Int. 1987;10(4):423-31. [Content Brief]
- [2]. G V Madhavan, et al. Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase. J Med Chem [Content Brief]
