1. Anti-infection
  2. HIV

2',3'-Dideoxyadenosine 

Cat. No.: HY-W013441
Handling Instructions

2',3'-Dideoxyadenosine is an inhibitor of HIV replication. Antiretroviral activity. Antiviral efficacy.

For research use only. We do not sell to patients.

2',3'-Dideoxyadenosine Chemical Structure

2',3'-Dideoxyadenosine Chemical Structure

CAS No. : 4097-22-7

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10 mg USD 80 Get quote

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

2',3'-Dideoxyadenosine is an inhibitor of HIV replication[1]. Antiretroviral activity[1]. Antiviral efficacy[1].

IC50 & Target

HIV[1]

In Vitro

2',3'-Dideoxyadenosine inhibits HIV-1 and simian immunodeficiency virus (SIV) in MT-4 cells with EC50s of 5.27 and 5.3 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in human T-lymphocyte CEM cells with EC50s of 4 μM and 8 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in Molt 4/C8 cells with EC50s of 4 μM and 5.5 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in C8166 cells with EC50s of 17 μM and 22 μM, respectively. 2',3'-Dideoxyadenosine inhibits murine sarcoma virus (MSV) in C3H/3T3 cells with an EC50 of 24 μM[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2510 mL 21.2549 mL 42.5098 mL
5 mM 0.8502 mL 4.2510 mL 8.5020 mL
10 mM 0.4251 mL 2.1255 mL 4.2510 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

235.24

Formula

C₁₀H₁₃N₅O₂

CAS No.

4097-22-7

SMILES

NC1=C(N=CN2[[email protected]]3CC[[email protected]](O3)CO)C2=NC=N1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
2',3'-Dideoxyadenosine
Cat. No.:
HY-W013441
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2',3'-Dideoxyadenosine

Cat. No.: HY-W013441