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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
O-Propargyl-Puromycin
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "O-Propargyl-Puromycin" in MCE Product Catalog:
33
33 Cited Publications
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O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Farudodstat (ASLAN003) is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for human DHODH enzyme. Farudodstat inhibits protein synthesis via activation of AP-1 transcription factors. Farudodstat induces apoptosis and substantially prolongs survival in acute myeloid leukemia (AML) xenograft mice .
Cat. No.: HY-D3581
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AF594 Picolyl Azide is a composite fluorescent probe formed by covalent linkage of the Alexa Fluor 594 fluorophore and the Picolyl Azide functional group via chemical bonds. AF594 Picolyl Azide contains a copper chelation domain, and through the copper-catalyzed azide-alkyne cycloaddition click chemistry reaction, it can covalently label alkyne-bearing target molecules and generate fluorescent detection signals. AF594 Picolyl Azide can be used for the detection of alkyne-modified sialylated glycoconjugates, and can also label nascent bacterial polypeptides to determine bacterial protein synthesis rates .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
