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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
PAK3
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "PAK3" in MCE Product Catalog:
10
Cat. No.: HY-RS00964
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ARHGEF7 Human Pre-designed siRNA Set A contains three designed siRNAs for ARHGEF7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09991
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Pak3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pak3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09990
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PAK3 Human Pre-designed siRNA Set A contains three designed siRNAs for PAK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09992
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Pak3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pak3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-146786
CAS No.: 2415295-37-1
ZMF-10 is a highly potent PAK1 inhibitor, with IC50s of 174 nM, 1.038 μM and 1.372 μM for PAK1, PAK2 and PAK3, respectively. ZMF-10 can inhibit PAK1 activity to affect PAK1-regulated apoptosis, ER-Stress and migration in MDA-MB-231 cells. ZMF-10 can be used for researching anticancer .
Cat. No.: HY-123739
CAS No.: 337500-87-5
LDN-0028574 is a PAK3 inhibitor. LDN-0028574 can be used in the research of p53-deficient cancers .
Cat. No.: HY-178812
CAS No.: 2098649-83-1
PI3Kα-IN-27 (Compound 50b) is an orally active PI3K-α inhibitor, with an IC50 of 40 nM. PI3Kα-IN-27 effectively inhibits PAK3, p110α, phospho-mTOR and phospho-ERK1/2. PI3Kα-IN-27 induces early Apoptosis. PI3Kα-IN-27 shows anticancer activity against pancreatic cancer, lung cancer, breast cancer .
Cat. No.: HY-184447
CAS No.: 3091508-49-2
RN193 is a type II kinase inhibitor with a human PAK1 IC50 of 4.28 μM. RN193 functionally inhibits kinase activity of PAK1, PAK2, and PAK3, and engages with their kinase domains in live cells. RN193 induces thermal shifts in CLK1, GSK3B, ULK1, MELK, MAPK13, BRAF, and STK10, indicating binding and stabilization of these proteins. RN193 induces formation of PAK3:PAK2 heterodimers and displaces PAK2 homodimers in live cells. RN193 acts as a tool compound for studying group I PAK conformational states .
Cat. No.: HY-P74654
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PAK3; HPAK3; Prev. MRX30; PAK-3; Prev. MRX47; Adriamycin Resistance-Associated; BPAK; Mental Retardation, X-Linked 47; P21 Protein (Cdc42/Rac)-Activated Kinase 3; P21-Activated Kinase 3; Serine/Threonine-Protein Kinase PAK 3; PAK3beta; P21 (CDKN1A)-Activa
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Cat. No.: HY-P702746
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PAK3; HPAK3; Prev. MRX30; PAK-3; Prev. MRX47; Adriamycin Resistance-Associated; BPAK; Mental Retardation, X-Linked 47; P21 Protein (Cdc42/Rac)-Activated Kinase 3; P21-Activated Kinase 3; Serine/Threonine-Protein Kinase PAK 3; PAK3beta; P21 (CDKN1A)-Activa
Species:
Source:
Cat. No.: HY-P705853
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PAK3; HPAK3; Prev. MRX30; PAK-3; Prev. MRX47; Adriamycin Resistance-Associated; BPAK; Mental Retardation, X-Linked 47; P21 Protein (Cdc42/Rac)-Activated Kinase 3; P21-Activated Kinase 3; Serine/Threonine-Protein Kinase PAK 3; PAK3beta; P21 (CDKN1A)-Activa
Species:
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Cat. No.: HY-118606
CAS No.: 296246-47-4
LDN-0044878 is a PAK3 inhibitor. LDN-0044878 inhibits the proliferation or induces the death of p53-deficient cells. LDN-0044878 exhibits moderate trypanocidal activity against Trypanosoma brucei, but does not directly inhibit the core target Rhodesain. LDN-0044878 can be used in studies related to cervical adenocarcinoma and Trypanosoma brucei infection.
Cat. No.: HY-P703253
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ARHGEF7; PAK3; Rho Guanine Nucleotide Exchange Factor 7; P50; P85SPR; Rho Guanine Nucleotide Exchange Factor (GEF) 7; COOL1; SH3 Domain-Containing Proline-Rich Protein; PIXB; DKFZp686C12170; P85; DKFZp761K1021; PAK-Interacting Exchange Factor Beta; COOL-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
