2415295-37-1
Chemical Structure
ZMF-10
- CAS No.: 2415295-37-1
- Formula:C19H17F6N7O
- Molecular Weight:473.37
IUPAC Name: 1-(1-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperidin-4-yl)-3-(3,5-bis(trifluoromethyl)phenyl)urea
InChIKey: KGUGNCJQOQZVJW-UHFFFAOYSA-N
SMILES: O=C(NC1CCN(CC1)C2=C3C=NNC3=NC=N2)NC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4
Biological Activity: ZMF-10 is a highly potent PAK1 inhibitor, with IC50s of 174 nM, 1.038 μM and 1.372 μM for PAK1, PAK2 and PAK3, respectively. ZMF-10 can inhibit PAK1 activity to affect PAK1-regulated apoptosis, ER-Stress and migration in MDA-MB-231 cells. ZMF-10 can be used for researching anticancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ZMF-10 | ZMF-10 is a highly potent PAK1 inhibitor, with IC50s of 174 nM, 1.038 μM and 1.372 μM for PAK1, PAK2 and PAK3, respectively. ZMF-10 can inhibit PAK1 activity to affect PAK1-regulated apoptosis, ER-Stress and migration in MDA-MB-231 cells. ZMF-10 can be used for researching anticancer. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
