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  4. ARHGEF7 Protein, Human (His, Strep)

ARHGEF7 Protein, Human (His, Strep) is the recombinant human-derived ARHGEF7, expressed by E. coli, with Strep, His labeled tag.

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Descripciòn

ARHGEF7 Protein, Human (His, Strep) is the recombinant human-derived ARHGEF7, expressed by E. coli, with Strep, His labeled tag.
Background

ARHGEF7 acts as a RAC1 guanine nucleotide exchange factor (GEF) and induces membrane ruffling. It functions in cell migration, attachment, and spreading, promoting RAC1 targeting to focal adhesions (by similar). Additionally, ARHGEF7 may serve as a positive regulator of apoptosis. Downstream of NMDA receptors and the CaMKK-CaMK1 signaling cascade, it facilitates spine and synapse formation in hippocampal neurons.
Species

Human
Source

E. coli
Tag

Strep;His
Accession

Q14155-4 (K260-R467)
Gene ID

8874
Protein Length

Partial
Synonyms
COOL1; KIAA0142; P85SPR; PAK3BP; PIXB
AA Sequence

KGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQILTEAIR

Predicted Molecular Mass
27 kDa
Pureza

≥ 90%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentación
Instrucciones de manejo (2659 KB)

ARHGEF7 Protein, Human (His, Strep) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Nombre del producto:
ARHGEF7 Protein, Human (His, Strep)
Cat. No.:
HY-P703253
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