1 Result for "

PARP7-IN-18

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PARP7-IN-18" in MCE Product Catalog:

Cat. No.: HY-162172
CAS No.: 2819999-00-1
Target:  

PARP

Research Areas:  

Cancer

PARP7-IN-18 is a potent, highly selective, and orally active PARP7 inhibitor with an IC50 of 0.11 nM. PARP7-IN-18 exhibits >1000-fold selectivity over other PARP family members. PARP7-IN-18 inhibits NCI-H1373 lung cancer cell proliferation with an IC50 of 2.5 nM and promotes IFN-β expression. PARP7-IN-18 exhibits favorable pharmacokinetic properties and can be used in research on PARP7-sensitive tumors, such as lung cancer .
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