1 Result for "

PD0325901 (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PD0325901 (Standard)" in MCE Product Catalog:

Cat. No.: HY-10254R
CAS No.: 391210-10-9
Synonyms: PD0325901 (Standard); PD325901 (Standard)
Research Areas:  

Cancer

Mirdametinib (Standard) is the analytical standard of Mirdametinib (HY-10254). This product is intended for research and analytical applications. Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts .
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