34 Results for "

PDGFRB

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "PDGFRB" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-132166
CAS No.: 2590556-80-0
Purity:  99.47%
Synonyms: M4205; IDRX-42
Target:  

c-Kit PDGFR c-Fms FLT3 Src

Research Areas:  

Cancer

Velzatinib (M4205) is a multi-target inhibitor for PDGFRB, PDGFRA, CSF1R, c-Kit, FLT3, and LCK, with an IC50s of 2.6, 50, 5.5, 44, 141 and 141 nM, respectively. Velzatinib exhibits antitumor efficacy in xenograft mouse models .
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Cat. No.: HY-15813
CAS No.: 1256152-35-8
Purity:  99.11%
Synonyms: FGFR irreversible inhibitor-1
Target:  

FGFR

Research Areas:  

Cancer

FIIN-1 is a potent, irreversible, selective FGFR inhibitor. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with Kds of 2.8/6.9/5.4/120 nM and 32/120 nM respectively. The biochemical IC50s of FIIN-1 are 9.2, 6.2, 11.9, and 189 nM against FGFR1/2/3/4, respectively .
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Cat. No.: HY-P990489
Synonyms: IMC-2C5

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-PDGFRB/CD140b Antibody (IMC-2C5) is a humanized antibody expressed in CHO cells that targets PDGFRB/CD140b. Anti-PDGFRB/CD140b Antibody (IMC-2C5) contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145.54 kDa. The isotype control for Anti-PDGFRB/CD140b Antibody (IMC-2C5) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-RS10257
Research Areas:  

Others

PDGFRB Human Pre-designed siRNA Set A contains three designed siRNAs for PDGFRB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS10258
Research Areas:  

Others

Pdgfrb Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pdgfrb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174548
Target:  

mRNA

Research Areas:  

Cancer

Human PDGFRB mRNA encodes the human platelet derived growth factor receptor beta (PDGFRB) protein, a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRB is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton.
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Cat. No.: HY-RS10259
Research Areas:  

Others

Pdgfrb Rat Pre-designed siRNA Set A contains three designed siRNAs for Pdgfrb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P74644
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
Species:  
Rat
Source:  
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Cat. No.: HY-P703816
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
Species:  
Source:  
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Cat. No.: HY-P73360
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
Species:  
Rat
Source:  
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Cat. No.: HY-P84032
Synonyms: JTK12; PDGFR; CD140B; PDGFR1; PDGFRB

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Mouse

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Cat. No.: HY-P84032A
Synonyms: JTK12; PDGFR; CD140B; PDGFR1; PDGFRB

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Mouse

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Cat. No.: HY-P77127
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
Species:  
Source:  
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Cat. No.: HY-P77129
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
Species:  
Source:  
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Cat. No.: HY-P77128
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
Species:  
Source:  
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Cat. No.: HY-P72494
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
Species:  
Source:  
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Cat. No.: HY-P77124
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
Species:  
Source:  
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Cat. No.: HY-P77123
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
Species:  
Source:  
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Cat. No.: HY-P992326

Target:  

PDGFR

Research Areas:  

Inflammation/Immunology Cancer

BOT1711 is a human IgG1κ monoclonal antibody targeting PDGFRB/CD140b. PDGFRB/CD140b belongs to type I receptor tyrosine kinases (RTKs), and is mainly expressed in vascular smooth muscle cells, pericytes, fibroblasts, certain mesenchymal stem cells, and tumor stromal cells.
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Cat. No.: HY-P78194
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: JTK12; PDGF R beta; PDGFR; PDGFR1; PDGFRB; CD140B; PDGFR-2; PDGFR-β; PDGF R β
Species:  
Source:  
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