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  4. PDGFs & PDGFRs Platelet CD Proteins Endothelial cell CD Proteins Receptor Tyrosine Kinases Cytokine Receptors Protein Tyrosine Kinases
  5. PDGFR
  6. PDGF-R-beta
  7. PDGF R beta Protein, Canine (HEK293, His)

PDGF R beta Protein is a tyrosine protein kinase that plays an important role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. PDGF R beta Protein, Canine (HEK293, His) is the recombinant canine-derived PDGF R beta protein, expressed by HEK293 , with C-His labeled tag.

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PDGF R beta Protein is a tyrosine protein kinase that plays an important role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. PDGF R beta Protein, Canine (HEK293, His) is the recombinant canine-derived PDGF R beta protein, expressed by HEK293 , with C-His labeled tag.
Background

PDGF R beta Protein is essential in embryonic development, regulating cell proliferation, survival, differentiation, chemotaxis, and migration. It plays a pivotal role in blood vessel development by promoting pericyte and smooth muscle cell proliferation, migration, and recruitment to endothelial cells. Additionally, it contributes to vascular smooth muscle cell migration and neointima formation at vascular injury sites.
Species

Canine
Source

HEK293
Tag

C-8*His
Accession

Q6QNF3 (G32-V532)
Gene ID
Molecular Construction
N-term
PDGF R beta (G32-V532)
Accession # Q6QNF3
8*His
C-term
Protein Length

Partial
Synonyms
JTK12; PDGF R beta; PDGFR; PDGFR1; PDGFRB; CD140B; PDGFR-2; PDGFR-β; PDGF R β
AA Sequence

GLVITPPGPELVLNISSTFVLTCSGPAPVVWERLSQEPLQKMARTQDGTFSSTLTLTNVTGLDTGEYFCTYKGSHGLEPDGRKRLYIFVPDPTMGFLPVDPEELFIFLTEITEITIPCRVTDPRLVVTLHEKKVDIPLPIPYDHQRGFSGTFEDKTYVCKTTIGDKEVDSEAYYVYSLQVSSINVSVNAVQTVVRQGENITIMCIVTGNEVVNFEWTYPRMESGRLVEPVTDFLFNVPSHIRSILHIPSAELGDSGTYICNVSESVNDHRDEKSINVTVVESGYVRLLGELDAVQFAELHRSRALQVVFEAYPPPTVVWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGYYTMRAFHEDAEAQLSFQLQVNVPVRVLELSESHPASGEQTVRCRGRGMPQPHLTWSTCSDLKRCPRELPPTPLGNSSEEESQLETNVTYWPEDQEFEVVSTLRLRRVDQPLSVRCTLHNLLGHDMQEVTVVPHSLPFKV

Predicted Molecular Mass
57.3 kDa
분자량

Approximately 70-100 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Glycosylation
Yes
Purity

≥ 95%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
각종 서류
Handling Instructions (2659 KB)

PDGF R beta Protein, Canine (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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PDGF R beta Protein, Canine (HEK293, His)
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