PDGF R beta Protein, Canine (HEK293, His)
PDGF R beta Protein is a tyrosine protein kinase that plays an important role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. PDGF R beta Protein, Canine (HEK293, His) is the recombinant canine-derived PDGF R beta protein, expressed by HEK293 , with C-His labeled tag.
- Species: Canine
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
PDGF R beta Protein is a tyrosine protein kinase that plays an important role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. PDGF R beta Protein, Canine (HEK293, His) is the recombinant canine-derived PDGF R beta protein, expressed by HEK293 , with C-His labeled tag.
Background
PDGF R beta Protein is essential in embryonic development, regulating cell proliferation, survival, differentiation, chemotaxis, and migration. It plays a pivotal role in blood vessel development by promoting pericyte and smooth muscle cell proliferation, migration, and recruitment to endothelial cells. Additionally, it contributes to vascular smooth muscle cell migration and neointima formation at vascular injury sites.
Technical Parameters
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Species Canine
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Source HEK293
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Tag C-8*His
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Accession
Q6QNF3 (G32-V532)
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Molecular Construction
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N-term
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PDGF R beta (G32-V532)
Accession # Q6QNF3 -
8*His
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C-term
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Protein Length
Extracellular Domain
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Synonyms
PDGFRB; PDGFR-Beta; Prev. PDGFR; Beta Platelet-Derived Growth Factor Receptor; PDGFR1; Activated Tyrosine Kinase PDGFRB; CD140b; CD140b Antigen; JTK12; NDEL1-PDGFRB; Platelet-Derived Growth Factor Receptor, Beta Polypeptide; IBGC4; Beta-Type Platelet-Deri
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AA Sequence
GLVITPPGPELVLNISSTFVLTCSGPAPVVWERLSQEPLQKMARTQDGTFSSTLTLTNVTGLDTGEYFCTYKGSHGLEPDGRKRLYIFVPDPTMGFLPVDPEELFIFLTEITEITIPCRVTDPRLVVTLHEKKVDIPLPIPYDHQRGFSGTFEDKTYVCKTTIGDKEVDSEAYYVYSLQVSSINVSVNAVQTVVRQGENITIMCIVTGNEVVNFEWTYPRMESGRLVEPVTDFLFNVPSHIRSILHIPSAELGDSGTYICNVSESVNDHRDEKSINVTVVESGYVRLLGELDAVQFAELHRSRALQVVFEAYPPPTVVWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGYYTMRAFHEDAEAQLSFQLQVNVPVRVLELSESHPASGEQTVRCRGRGMPQPHLTWSTCSDLKRCPRELPPTPLGNSSEEESQLETNVTYWPEDQEFEVVSTLRLRRVDQPLSVRCTLHNLLGHDMQEVTVVPHSLPFKV
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Predicted Molecular Mass
57.3 kDa
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Molecular Weight
Approximately 70-100 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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